Sourcing quality-of-life weights obtained from previous studies: Theory and reality in Korea

Seung Jin Bae, Eun Young Bae, Sang Hee Lim

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Background: The quality-of-life weights obtained in previous studies are frequently used in cost-utility analyses. The purpose of this study is to describe how the values obtained in previous studies are incorporated into the industry submissions requesting listing at the Korean National Health Insurance (NHI), focusing on the issues discussed in theoretical studies and national guidelines. Methods: The industry submissions requesting listing at the Korean NHI from January 2007 until December 2009 were evaluated by two independent researchers at the Health Insurance Review and Assessment Service (HIRA). Specifically, we observed the methods that were used to pool, predict joint health state utilities, and retain consistency within submissions in terms of the issues discussed in methodological research papers and recommendations from national guidelines. Results: More than half of the submissions used QALY as an outcome measure, and most of these submissions were sourced from prior studies. Heterogeneous methodologies were frequently used within a submission, with the inconsistent use of upper and lower anchors being prevalent. Assumptions behind measuring joint health state utilities or pooling multiple values for single health states were omitted in all submissions. Most national guidelines were rather vague regarding how to predict joint health states, how to select the best available value, how to maintain consistency within a submission, and how to generalize values obtained from prior studies. Conclusions: Previously-generated values were commonly sourced, but this practice was frequently related to inconsistencies within and among submissions. Attention should be paid to the consistency and transparency of the value, especially if the value is sourced from prior studies.

Original languageEnglish
Pages (from-to)141-150
Number of pages10
Issue number2
StatePublished - Jun 2014

Bibliographical note

Funding Information:
Acknowledgments This study was financially supported by the HIRA in Seoul, Korea. SeungJin Bae was the principal investigator of the project at the HIRA. SeungJin Bae and Sang Hee Lim were involved with the project, and were employed at the HIRA throughout the study period. Eun Young Bae has served as a member of the DREC since 2011 and the economic subcommittee of the DREC since 2009. SeungJin Bae has served on the economic subcommittee of the DREC since 2013. The authors are grateful to two anonymous reviewers for their helpful comments.


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