Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media

Ikuo Nakanishi; Kei Ohkubo; Kohei Imai; Masato Kamibayashi; Yasuo Yoshihashi; Ken Ichiro Matsumoto; Kiyoshi Fukuhara; Katsuhide Terada; Shinobu Itoh; Toshihiko Ozawa; Shunichi Fukuzumi

doi:10.1039/c5cc02236c

Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media

Ikuo Nakanishi
, Kei Ohkubo
, Kohei Imai
, Masato Kamibayashi
, Yasuo Yoshihashi
, Ken Ichiro Matsumoto
, Kiyoshi Fukuhara
, Katsuhide Terada
, Shinobu Itoh
, Toshihiko Ozawa
, Shunichi Fukuzumi

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

A 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) was successfully solubilised in water by β-cyclodextrin (β-CD). DPPH/β-CD thus obtained was demonstrated to be a powerful tool to evaluate the antioxidative activity of water-soluble antioxidants, such as ascorbate and Trolox, in aqueous buffer solutions.

Original language	English
Pages (from-to)	8311-8314
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	39
DOIs	https://doi.org/10.1039/c5cc02236c
State	Published - 14 May 2015

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Publisher Copyright:
© The Royal Society of Chemistry 2015.

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Nakanishi, I., Ohkubo, K., Imai, K., Kamibayashi, M., Yoshihashi, Y., Matsumoto, K. I., Fukuhara, K., Terada, K., Itoh, S., Ozawa, T., & Fukuzumi, S. (2015). Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media. Chemical Communications, 51(39), 8311-8314. https://doi.org/10.1039/c5cc02236c

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title = "Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media",

abstract = "A 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) was successfully solubilised in water by β-cyclodextrin (β-CD). DPPH/β-CD thus obtained was demonstrated to be a powerful tool to evaluate the antioxidative activity of water-soluble antioxidants, such as ascorbate and Trolox, in aqueous buffer solutions.",

author = "Ikuo Nakanishi and Kei Ohkubo and Kohei Imai and Masato Kamibayashi and Yasuo Yoshihashi and Matsumoto, \{Ken Ichiro\} and Kiyoshi Fukuhara and Katsuhide Terada and Shinobu Itoh and Toshihiko Ozawa and Shunichi Fukuzumi",

note = "Publisher Copyright: {\textcopyright} The Royal Society of Chemistry 2015.",

year = "2015",

month = may,

day = "14",

doi = "10.1039/c5cc02236c",

language = "English",

volume = "51",

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Nakanishi, I, Ohkubo, K, Imai, K, Kamibayashi, M, Yoshihashi, Y, Matsumoto, KI, Fukuhara, K, Terada, K, Itoh, S, Ozawa, T & Fukuzumi, S 2015, 'Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media', Chemical Communications, vol. 51, no. 39, pp. 8311-8314. https://doi.org/10.1039/c5cc02236c

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T1 - Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media

AU - Nakanishi, Ikuo

AU - Ohkubo, Kei

AU - Imai, Kohei

AU - Kamibayashi, Masato

AU - Yoshihashi, Yasuo

AU - Matsumoto, Ken Ichiro

AU - Fukuhara, Kiyoshi

AU - Terada, Katsuhide

AU - Itoh, Shinobu

AU - Ozawa, Toshihiko

AU - Fukuzumi, Shunichi

PY - 2015/5/14

Y1 - 2015/5/14

N2 - A 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) was successfully solubilised in water by β-cyclodextrin (β-CD). DPPH/β-CD thus obtained was demonstrated to be a powerful tool to evaluate the antioxidative activity of water-soluble antioxidants, such as ascorbate and Trolox, in aqueous buffer solutions.

AB - A 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) was successfully solubilised in water by β-cyclodextrin (β-CD). DPPH/β-CD thus obtained was demonstrated to be a powerful tool to evaluate the antioxidative activity of water-soluble antioxidants, such as ascorbate and Trolox, in aqueous buffer solutions.

UR - https://www.scopus.com/pages/publications/84928958252

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DO - 10.1039/c5cc02236c

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SP - 8311

EP - 8314

JO - Chemical Communications

JF - Chemical Communications

IS - 39

ER -

Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media

Abstract

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