Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media

Ikuo Nakanishi; Kei Ohkubo; Kohei Imai; Masato Kamibayashi; Yasuo Yoshihashi; Ken Ichiro Matsumoto; Kiyoshi Fukuhara; Katsuhide Terada; Shinobu Itoh; Toshihiko Ozawa; Shunichi Fukuzumi

doi:10.1039/c5cc02236c

Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media

Ikuo Nakanishi, Kei Ohkubo, Kohei Imai, Masato Kamibayashi, Yasuo Yoshihashi, Ken Ichiro Matsumoto, Kiyoshi Fukuhara, Katsuhide Terada, Shinobu Itoh, Toshihiko Ozawa, Shunichi Fukuzumi

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

A 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) was successfully solubilised in water by β-cyclodextrin (β-CD). DPPH/β-CD thus obtained was demonstrated to be a powerful tool to evaluate the antioxidative activity of water-soluble antioxidants, such as ascorbate and Trolox, in aqueous buffer solutions.

Original language	English
Pages (from-to)	8311-8314
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	39
DOIs	https://doi.org/10.1039/c5cc02236c
State	Published - 14 May 2015

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Publisher Copyright:
© The Royal Society of Chemistry 2015.

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Nakanishi, I., Ohkubo, K., Imai, K., Kamibayashi, M., Yoshihashi, Y., Matsumoto, K. I., Fukuhara, K., Terada, K., Itoh, S., Ozawa, T., & Fukuzumi, S. (2015). Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media. Chemical Communications, 51(39), 8311-8314. https://doi.org/10.1039/c5cc02236c

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abstract = "A 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) was successfully solubilised in water by β-cyclodextrin (β-CD). DPPH/β-CD thus obtained was demonstrated to be a powerful tool to evaluate the antioxidative activity of water-soluble antioxidants, such as ascorbate and Trolox, in aqueous buffer solutions.",

author = "Ikuo Nakanishi and Kei Ohkubo and Kohei Imai and Masato Kamibayashi and Yasuo Yoshihashi and Matsumoto, {Ken Ichiro} and Kiyoshi Fukuhara and Katsuhide Terada and Shinobu Itoh and Toshihiko Ozawa and Shunichi Fukuzumi",

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month = may,

day = "14",

doi = "10.1039/c5cc02236c",

language = "English",

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Nakanishi, I, Ohkubo, K, Imai, K, Kamibayashi, M, Yoshihashi, Y, Matsumoto, KI, Fukuhara, K, Terada, K, Itoh, S, Ozawa, T & Fukuzumi, S 2015, 'Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media', Chemical Communications, vol. 51, no. 39, pp. 8311-8314. https://doi.org/10.1039/c5cc02236c

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T1 - Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media

AU - Nakanishi, Ikuo

AU - Ohkubo, Kei

AU - Imai, Kohei

AU - Kamibayashi, Masato

AU - Yoshihashi, Yasuo

AU - Matsumoto, Ken Ichiro

AU - Fukuhara, Kiyoshi

AU - Terada, Katsuhide

AU - Itoh, Shinobu

AU - Ozawa, Toshihiko

AU - Fukuzumi, Shunichi

PY - 2015/5/14

Y1 - 2015/5/14

N2 - A 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) was successfully solubilised in water by β-cyclodextrin (β-CD). DPPH/β-CD thus obtained was demonstrated to be a powerful tool to evaluate the antioxidative activity of water-soluble antioxidants, such as ascorbate and Trolox, in aqueous buffer solutions.

AB - A 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) was successfully solubilised in water by β-cyclodextrin (β-CD). DPPH/β-CD thus obtained was demonstrated to be a powerful tool to evaluate the antioxidative activity of water-soluble antioxidants, such as ascorbate and Trolox, in aqueous buffer solutions.

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ER -

Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media

Abstract

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