Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media

Ikuo Nakanishi, Kei Ohkubo, Kohei Imai, Masato Kamibayashi, Yasuo Yoshihashi, Ken Ichiro Matsumoto, Kiyoshi Fukuhara, Katsuhide Terada, Shinobu Itoh, Toshihiko Ozawa, Shunichi Fukuzumi

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Abstract

A 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) was successfully solubilised in water by β-cyclodextrin (β-CD). DPPH/β-CD thus obtained was demonstrated to be a powerful tool to evaluate the antioxidative activity of water-soluble antioxidants, such as ascorbate and Trolox, in aqueous buffer solutions.

Original languageEnglish
Pages (from-to)8311-8314
Number of pages4
JournalChemical Communications
Volume51
Issue number39
DOIs
StatePublished - 14 May 2015

Bibliographical note

Publisher Copyright:
© The Royal Society of Chemistry 2015.

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