TY - GEN
T1 - Single-layer "domino" diodes via optofluidic lithography for ultra-low Reynolds number applications
AU - Sochol, Ryan D.
AU - Glick, Casey C.
AU - Lee, Kye Y.
AU - Brubaker, Thomas
AU - Lu, Albert
AU - Wah, Melissa
AU - Gao, Shan
AU - Hicks, Erica
AU - Wolf, Ki Tae
AU - Iwai, Kosuke
AU - Lee, Luke P.
AU - Lin, Liwei
PY - 2013
Y1 - 2013
N2 - Autonomous fluidic components are critical to the advancement of integrated micro/nanofluidic circuitry for lab-on-a-chip applications, such as point-of-care (POC) molecular diagnostics and on-site chemical detection. Previously, a wide range of self-regulating microfluidic components, such as fluidic diodes, have been developed; however, achieving effective functionality at ultra-low Reynolds number (e.g., Re < 0.05) has remained a significant challenge. To overcome this issue, here we introduce single-layer microfluidic "domino" diodes, which utilize free-standing rotational microstructures - constructed in situ via optofluidic lithography - in order to passively regulate the fluidic resistance based on the flow polarity, thereby enabling flow rectification under ultra-low Re conditions. COMSOL simulation results revealed a theoretical Diodicity (Di) of 31 for a singular domino diode component. Experimental results (for systems with four microstructures) revealed Di's ranging from 13.0±1.9 to 25.4±1.9 corresponding to 0.025 < Re < 0.030 and 0.010 < Re < 0.015 flow, respectively, which represent the largest Di's reported for Re < 0.05 fluid flow.
AB - Autonomous fluidic components are critical to the advancement of integrated micro/nanofluidic circuitry for lab-on-a-chip applications, such as point-of-care (POC) molecular diagnostics and on-site chemical detection. Previously, a wide range of self-regulating microfluidic components, such as fluidic diodes, have been developed; however, achieving effective functionality at ultra-low Reynolds number (e.g., Re < 0.05) has remained a significant challenge. To overcome this issue, here we introduce single-layer microfluidic "domino" diodes, which utilize free-standing rotational microstructures - constructed in situ via optofluidic lithography - in order to passively regulate the fluidic resistance based on the flow polarity, thereby enabling flow rectification under ultra-low Re conditions. COMSOL simulation results revealed a theoretical Diodicity (Di) of 31 for a singular domino diode component. Experimental results (for systems with four microstructures) revealed Di's ranging from 13.0±1.9 to 25.4±1.9 corresponding to 0.025 < Re < 0.030 and 0.010 < Re < 0.015 flow, respectively, which represent the largest Di's reported for Re < 0.05 fluid flow.
UR - https://www.scopus.com/pages/publications/84875432661
U2 - 10.1109/MEMSYS.2013.6474200
DO - 10.1109/MEMSYS.2013.6474200
M3 - Conference contribution
AN - SCOPUS:84875432661
SN - 9781467356558
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 153
EP - 156
BT - IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
T2 - IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Y2 - 20 January 2013 through 24 January 2013
ER -