Single cell differential impedance spectroscopy analysis using high density hydrodynamic cell trapping arrays

Daniele Malleo; Dino Di Carlo; J. Tanner Nevill; David Holmes; Luke P. Lee; Hywel Morgan

Single cell differential impedance spectroscopy analysis using high density hydrodynamic cell trapping arrays

Daniele Malleo, Dino Di Carlo, J. Tanner Nevill, David Holmes, Luke P. Lee, Hywel Morgan

Department of Chemistry & Nanoscience

Research output: Contribution to conference › Paper › peer-review

1 Scopus citations

Abstract

We present a novel device for performing differential impedance spectroscopic analysis of single cells hydrodynamically captured in an array of trapping sites. The method combines the advantages offered by impedimetric analysis used for flow cytometry with the ability to capture multiple single cells and perform long-term transient and steady state analysis. We have tested the device by capturing single polystyrene beads and HeLa cells and measuring differential impedance responses.

Original language	English
Pages	1292-1294
Number of pages	3
State	Published - 2006
Event	10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan Duration: 5 Nov 2006 → 9 Nov 2006

Conference

Conference	10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
Country/Territory	Japan
City	Tokyo
Period	5/11/06 → 9/11/06

Keywords

Differential impedance spectroscopy
Single cell analysis

Cite this

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title = "Single cell differential impedance spectroscopy analysis using high density hydrodynamic cell trapping arrays",

abstract = "We present a novel device for performing differential impedance spectroscopic analysis of single cells hydrodynamically captured in an array of trapping sites. The method combines the advantages offered by impedimetric analysis used for flow cytometry with the ability to capture multiple single cells and perform long-term transient and steady state analysis. We have tested the device by capturing single polystyrene beads and HeLa cells and measuring differential impedance responses.",

keywords = "Differential impedance spectroscopy, Single cell analysis",

author = "Daniele Malleo and {Di Carlo}, Dino and Nevill, {J. Tanner} and David Holmes and Lee, {Luke P.} and Hywel Morgan",

year = "2006",

language = "English",

pages = "1292--1294",

note = "10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 ; Conference date: 05-11-2006 Through 09-11-2006",

}

Single cell differential impedance spectroscopy analysis using high density hydrodynamic cell trapping arrays. / Malleo, Daniele; Di Carlo, Dino; Nevill, J. Tanner et al.
2006. 1292-1294 Paper presented at 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006, Tokyo, Japan.

Research output: Contribution to conference › Paper › peer-review

TY - CONF

T1 - Single cell differential impedance spectroscopy analysis using high density hydrodynamic cell trapping arrays

AU - Malleo, Daniele

AU - Di Carlo, Dino

AU - Nevill, J. Tanner

AU - Holmes, David

AU - Lee, Luke P.

AU - Morgan, Hywel

PY - 2006

Y1 - 2006

N2 - We present a novel device for performing differential impedance spectroscopic analysis of single cells hydrodynamically captured in an array of trapping sites. The method combines the advantages offered by impedimetric analysis used for flow cytometry with the ability to capture multiple single cells and perform long-term transient and steady state analysis. We have tested the device by capturing single polystyrene beads and HeLa cells and measuring differential impedance responses.

AB - We present a novel device for performing differential impedance spectroscopic analysis of single cells hydrodynamically captured in an array of trapping sites. The method combines the advantages offered by impedimetric analysis used for flow cytometry with the ability to capture multiple single cells and perform long-term transient and steady state analysis. We have tested the device by capturing single polystyrene beads and HeLa cells and measuring differential impedance responses.

KW - Differential impedance spectroscopy

KW - Single cell analysis

UR - http://www.scopus.com/inward/record.url?scp=84902456473&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:84902456473

SP - 1292

EP - 1294

T2 - 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006

Y2 - 5 November 2006 through 9 November 2006

ER -

Single cell differential impedance spectroscopy analysis using high density hydrodynamic cell trapping arrays

Abstract

Conference

Keywords

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Cite this