Abstract
A 24-year old woman presented with hemorrhagic vesicles on her legs. She had taken sibutramine (Reductil® , Abbott Labs., Seoul, South Korea) for 3 months and developed skin lesions the week before. A skin biopsy showed leukocytoclastic vasculitis with conspicuous eosinophilic infiltration of the tissue. These lesions showed improvement after discontinuation of sibutramine. However, 3 months later the skin lesions recurred on other sites on the lower extremities when the patient was rechallenged with the same drug for 2 weeks. Herein, we report the first case of necrotizing vasculitis induced by sibutramine.
Original language | English |
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Pages (from-to) | 544-547 |
Number of pages | 4 |
Journal | Annals of Dermatology |
Volume | 23 |
Issue number | 4 |
DOIs | |
State | Published - Nov 2011 |
Keywords
- Cutaneous leukocytoclastic vasculitis
- Drug induced vasculitis
- Sibutramine