Serum BAFF expression in patients with myasthenia gravis

Jee Young Kim; Young Yang; Joon Shik Moon; Eun Young Lee; Sun Hwha So; Hong Soo Lee; Kee Duk Park; Young Chul Choi

doi:10.1016/j.jneuroim.2008.05.010

Serum BAFF expression in patients with myasthenia gravis

Jee Young Kim, Young Yang, Joon Shik Moon, Eun Young Lee, Sun Hwha So, Hong Soo Lee, Kee Duk Park, Young Chul Choi

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

A B-cell activating factor of the tumor necrosis factor (TNF) family (BAFF) is an essential B-cell survival factor. Myasthenia gravis (MG) is one of the most typical antibody-mediated autoimmune disorders. To test whether serum BAFF levels are increased in MG patients, we compared the serum BAFF levels of 40 MG patients with those of 30 healthy controls. Serum BAFF levels of MG group were significantly higher than those of healthy group. These results suggested that the BAFF might play a role in the immunopathogenesis of MG and further study on B-cell and T-cell activation may be needed.

Original language	English
Pages (from-to)	151-154
Number of pages	4
Journal	Journal of Neuroimmunology
Volume	199
Issue number	1-2
DOIs	https://doi.org/10.1016/j.jneuroim.2008.05.010
State	Published - 13 Aug 2008

Keywords

B lymphocyte stimulator
BAFF
Myasthenia gravis (MG)

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10.1016/j.jneuroim.2008.05.010

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title = "Serum BAFF expression in patients with myasthenia gravis",

abstract = "A B-cell activating factor of the tumor necrosis factor (TNF) family (BAFF) is an essential B-cell survival factor. Myasthenia gravis (MG) is one of the most typical antibody-mediated autoimmune disorders. To test whether serum BAFF levels are increased in MG patients, we compared the serum BAFF levels of 40 MG patients with those of 30 healthy controls. Serum BAFF levels of MG group were significantly higher than those of healthy group. These results suggested that the BAFF might play a role in the immunopathogenesis of MG and further study on B-cell and T-cell activation may be needed.",

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T1 - Serum BAFF expression in patients with myasthenia gravis

AU - Kim, Jee Young

AU - Yang, Young

AU - Moon, Joon Shik

AU - Lee, Eun Young

AU - So, Sun Hwha

AU - Lee, Hong Soo

AU - Park, Kee Duk

AU - Choi, Young Chul

PY - 2008/8/13

Y1 - 2008/8/13

N2 - A B-cell activating factor of the tumor necrosis factor (TNF) family (BAFF) is an essential B-cell survival factor. Myasthenia gravis (MG) is one of the most typical antibody-mediated autoimmune disorders. To test whether serum BAFF levels are increased in MG patients, we compared the serum BAFF levels of 40 MG patients with those of 30 healthy controls. Serum BAFF levels of MG group were significantly higher than those of healthy group. These results suggested that the BAFF might play a role in the immunopathogenesis of MG and further study on B-cell and T-cell activation may be needed.

AB - A B-cell activating factor of the tumor necrosis factor (TNF) family (BAFF) is an essential B-cell survival factor. Myasthenia gravis (MG) is one of the most typical antibody-mediated autoimmune disorders. To test whether serum BAFF levels are increased in MG patients, we compared the serum BAFF levels of 40 MG patients with those of 30 healthy controls. Serum BAFF levels of MG group were significantly higher than those of healthy group. These results suggested that the BAFF might play a role in the immunopathogenesis of MG and further study on B-cell and T-cell activation may be needed.

KW - B lymphocyte stimulator

KW - BAFF

KW - Myasthenia gravis (MG)

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JF - Journal of Neuroimmunology

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ER -

Serum BAFF expression in patients with myasthenia gravis

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Keywords

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