Sensors for In Situ Real-Time Fluorescence Imaging of Enzymes

Xiaofeng Wu, Haidong Li, Eunhye Lee, Juyoung Yoon

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations

Abstract

Challenges and opportunities: • In situ real-time fluorescence imaging is an extremely useful method for researchers to observe the dynamics of enzymes and their interactions with other species in the biosystem • Developing new methods with high binding efficiency toward enzyme for in situ real-time imaging enzyme remains a great challenge • Enzyme- and photoactivatable fluorescent sensors bearing a diazoindanone moiety may prove to be a promising tool for in situ real-time imaging with high resolution of enzymes

Original languageEnglish
Pages (from-to)2893-2901
Number of pages9
JournalChem
Volume6
Issue number11
DOIs
StatePublished - 5 Nov 2020

Keywords

  • SDG3: Good health and well-being
  • dynamics
  • enzymes
  • fluorescence imaging
  • in situ
  • real-time

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