Self-assembly of block copolymers for biological applications

Zili Li, Zhiqun Lin

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Self-assembly of block copolymers (BCPs) has garnered much attention over the past several decades owing to an array of intriguing properties. In this perspective, recent advances in self-assembly and applications of BCPs with different architectures are presented. First, the self-assembly mechanism of BCPs and the general criteria to evaluate the assembled morphologies are introduced. Subsequently, the self-assembly of linear, star-like and bottlebrush-like BCPs is discussed. In particular, polymerization-induced self-assembly for large-scale preparation is highlighted. Afterwards, a rich diversity of applications of self-assembled BCPs in drug delivery, bioimaging, molecular recognition and photothermal therapy are outlined. Finally, an outlook on larger-scale production and implementation of self-assembled BCPs for biological applications is noted.

Original languageEnglish
Pages (from-to)366-370
Number of pages5
JournalPolymer International
Issue number4
StatePublished - Apr 2022

Bibliographical note

Publisher Copyright:
© 2021 Society of Industrial Chemistry.


  • biological applications
  • bottlebrush-like block copolymers
  • self-assembly
  • star-like block copolymers


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