TY - JOUR
T1 - Self-assembly of block copolymers for biological applications
AU - Li, Zili
AU - Lin, Zhiqun
N1 - Funding Information:
This work is supported by the Air Force Office of Scientific Research (FA9550‐19‐1‐0317) and NSF (CMMI 1914713, Chemistry 1903957).
Publisher Copyright:
© 2021 Society of Industrial Chemistry.
PY - 2022/4
Y1 - 2022/4
N2 - Self-assembly of block copolymers (BCPs) has garnered much attention over the past several decades owing to an array of intriguing properties. In this perspective, recent advances in self-assembly and applications of BCPs with different architectures are presented. First, the self-assembly mechanism of BCPs and the general criteria to evaluate the assembled morphologies are introduced. Subsequently, the self-assembly of linear, star-like and bottlebrush-like BCPs is discussed. In particular, polymerization-induced self-assembly for large-scale preparation is highlighted. Afterwards, a rich diversity of applications of self-assembled BCPs in drug delivery, bioimaging, molecular recognition and photothermal therapy are outlined. Finally, an outlook on larger-scale production and implementation of self-assembled BCPs for biological applications is noted.
AB - Self-assembly of block copolymers (BCPs) has garnered much attention over the past several decades owing to an array of intriguing properties. In this perspective, recent advances in self-assembly and applications of BCPs with different architectures are presented. First, the self-assembly mechanism of BCPs and the general criteria to evaluate the assembled morphologies are introduced. Subsequently, the self-assembly of linear, star-like and bottlebrush-like BCPs is discussed. In particular, polymerization-induced self-assembly for large-scale preparation is highlighted. Afterwards, a rich diversity of applications of self-assembled BCPs in drug delivery, bioimaging, molecular recognition and photothermal therapy are outlined. Finally, an outlook on larger-scale production and implementation of self-assembled BCPs for biological applications is noted.
KW - biological applications
KW - bottlebrush-like block copolymers
KW - self-assembly
KW - star-like block copolymers
UR - http://www.scopus.com/inward/record.url?scp=85120357930&partnerID=8YFLogxK
U2 - 10.1002/pi.6327
DO - 10.1002/pi.6327
M3 - Article
AN - SCOPUS:85120357930
SN - 0959-8103
VL - 71
SP - 366
EP - 370
JO - Polymer International
JF - Polymer International
IS - 4
ER -