Selective fluorescent and colorimetric recognition of cyanide via altering hydrogen bonding interaction in aqueous solution and its application in bioimaging

Xin Zhou, Jaemee Kim, Zhixue Liu, Sunjung Jo, Yen Leng Pak, K. M.K. Swamy, Juyoung Yoon

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

In this paper, we report a new pyrene imine derivative which bears a relatively rigid intramolecular hydrogen bonding pocket, for fluorescent and colorimetric sensing of cyanide. In CH3CN solution, the chemosensor displayed distinct fluorescent and UV absorption changes towards CN-, CH3CO2-, F-, and H2PO4-. Notably, in an aqueous CH3CN medium (10%, v/v), the selectivity towards cyanide over other various anions were observed with an obvious fluorescence enhancement and colorimetric change. Thus, we demonstrated that the selectivity of the pyrene based chemosensor towards anions can be optimized via controlling hydrogen bonding interactions in different solvent systems. Finally the application of the chemosensor in fluorescent imaging cellular cyanide variation was demonstrated with living HeLa cells.

Original languageEnglish
Pages (from-to)256-262
Number of pages7
JournalDyes and Pigments
Volume128
DOIs
StatePublished - 1 May 2016

Keywords

  • Cell imaging
  • Colorimetric sensor
  • Cyanide sensor
  • Fluorescent sensor
  • Hydrogen bonding
  • Pyrene

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