TY - GEN
T1 - Satellite nanoscope and cellular BioASICs for quantitative biomedicine
AU - Lee, Luke P.
PY - 2009
Y1 - 2009
N2 - This paper presents satellite nanoscopes and biological application specific integrated circuits (BioASICs). Satellite nanoscope is developed for spectroscopic imaging of living cells, molecular optogenetics (i.e. the remote control of gene regulation and protein expression), and therapeutic applications. Fundamental understanding of living cells via satellite nanoscopes will provide insights of molecular dynamics and signaling pathways in living cells. BioASICs are accomplished to permit precise and repeatable characterizations of cellular activity. These BioASICs are facilitating significant advancements in quantitative cell biology and the foundation for precision biology, cell reprogramming, high-speed biologic microprocessors, drug screening, molecular diagnostics, and personalized medicine.
AB - This paper presents satellite nanoscopes and biological application specific integrated circuits (BioASICs). Satellite nanoscope is developed for spectroscopic imaging of living cells, molecular optogenetics (i.e. the remote control of gene regulation and protein expression), and therapeutic applications. Fundamental understanding of living cells via satellite nanoscopes will provide insights of molecular dynamics and signaling pathways in living cells. BioASICs are accomplished to permit precise and repeatable characterizations of cellular activity. These BioASICs are facilitating significant advancements in quantitative cell biology and the foundation for precision biology, cell reprogramming, high-speed biologic microprocessors, drug screening, molecular diagnostics, and personalized medicine.
KW - Biophotonics
KW - Cell culture chip
KW - Microfluidics
KW - Molecular diagnostics
KW - Molecular optogenetics
KW - NASBA
KW - Nanoplasmonics
KW - Nanoscope
KW - ONCOS
KW - Personalized medicine
KW - Quantitative biology
KW - Spectroscopic imaging
UR - http://www.scopus.com/inward/record.url?scp=77950971385&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2009.5332763
DO - 10.1109/IEMBS.2009.5332763
M3 - Conference contribution
C2 - 19963844
AN - SCOPUS:77950971385
SN - 9781424432967
T3 - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
SP - 4582
EP - 4585
BT - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
PB - IEEE Computer Society
T2 - 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
Y2 - 2 September 2009 through 6 September 2009
ER -