Salicylimine-based fluorescent chemosensor for aluminum ions and application to bioimaging

Soojin Kim, Jin Young Noh, Ka Young Kim, Jin Hoon Kim, Hee Kyung Kang, Seong Won Nam, So Hyun Kim, Sungsu Park, Cheal Kim, Jinheung Kim

Research output: Contribution to journalArticlepeer-review

335 Scopus citations


In this study, an assay to quantify the presence of aluminum ions using a salicylimine-based receptor was developed utilizing turn-on fluorescence enhancement. Upon treatment with aluminum ions, the fluorescence of the sensor was enhanced at 510 nm due to formation of a 1:1 complex between the chemosensor and the aluminum ions at room temperature. As the concentration of Al 3+ was increased, the fluorescence gradually increased. Other metal ions, such as Na +, Ag +, K +, Ca 2+, Mg 2+, Hg 2+, Mn 2+, Co 2+, Ni 2+, Cu 2+, Zn 2+, Cd 2+, Pb 2+, Cr 3+, Fe 3+, and In 3+, had no such significant effect on the fluorescence. In addition, we show that the probe could be used to map intracellular Al 3+ distribution in live cells by confocal microscopy.

Original languageEnglish
Pages (from-to)3597-3602
Number of pages6
JournalInorganic Chemistry
Issue number6
StatePublished - 19 Mar 2012


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