Roles of ERK and p38 mitogen-activated protein kinases in phorbol ester-induced NF-κB activation and COX-2 expression in human breast epithelial cells

Medicine & Life Sciences

• Phorbol Esters 81%
• Cyclooxygenase 2 77%
• p38 Mitogen-Activated Protein Kinases 76%
• Tetradecanoylphorbol Acetate 65%
• Breast 56%
• Epithelial Cells 52%
• pyrrolidine dithiocarbamic acid 10%
• SB 203580 9%
• 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one 8%
• DNA 8%
• Chemoprevention 8%
• Protein Kinase Inhibitors 7%
• Mitogens 7%
• Reporter Genes 7%
• Dinoprostone 7%
• Carcinogens 7%
• Luciferases 6%
• Carcinogenesis 5%
• Transcription Factors 5%
• Up-Regulation 5%
• Phosphorylation 5%
• Neoplasms 4%
• Breast Neoplasms 4%
• Cell Line 4%
• Messenger RNA 4%
• Therapeutics 3%
• Proteins 2%

Chemical Compounds

• Phorbol 100%
• EC 2.7.12.2 (Mitogen-Activated Protein Kinase Kinase) Inhibitor 39%
• Pyrrolidine Dithiocarbamate 37%
• Tumor Promoter 36%
• Mitogen 34%
• Prostaglandin E2 33%
• Protein 30%