TY - JOUR
T1 - Risk factors for death during pulmonary tuberculosis treatment in Korea
T2 - A multicenter retrospective cohort study
AU - Kwon, Yong Soo
AU - Kim, Yee Hyung
AU - Song, Jae Uk
AU - Jeon, Kyeongman
AU - Song, Junwhi
AU - Ryu, Yon Ju
AU - Choi, Jae Chol
AU - Kim, Ho Cheol
AU - Koh, Won Jung
N1 - Publisher Copyright:
© 2014 The Korean Academy of Medical Sciences.
PY - 2014
Y1 - 2014
N2 - The data regarding risk factors for death during tuberculosis (TB) treatment are inconsistent, and few studies examined this issue in Korea. The purpose of this study was to evaluate baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea. A multicenter retrospective cohort study of 2,481 patients who received TB treatment at eight hospitals from January 2009 to December 2010 was performed. Successful treatment included cure (1,129, 45.5%) and treatment completion (1,204, 48.5%) in 2,333 patients (94.0%). Unsuccessful treatment included death (85, 3.4%) and treatment failure (63, 2.5%) occurred in 148 patients (6.0%). In multivariate analysis, male sex, anemia, dyspnea, chronic heart disease, malignancy, and intensive care unit (ICU) admission were significant risk factors for death during TB treatment. Therefore, male sex, anemia, dyspnea, chronic heart disease, malignancy, and ICU admission could be baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea.
AB - The data regarding risk factors for death during tuberculosis (TB) treatment are inconsistent, and few studies examined this issue in Korea. The purpose of this study was to evaluate baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea. A multicenter retrospective cohort study of 2,481 patients who received TB treatment at eight hospitals from January 2009 to December 2010 was performed. Successful treatment included cure (1,129, 45.5%) and treatment completion (1,204, 48.5%) in 2,333 patients (94.0%). Unsuccessful treatment included death (85, 3.4%) and treatment failure (63, 2.5%) occurred in 148 patients (6.0%). In multivariate analysis, male sex, anemia, dyspnea, chronic heart disease, malignancy, and intensive care unit (ICU) admission were significant risk factors for death during TB treatment. Therefore, male sex, anemia, dyspnea, chronic heart disease, malignancy, and ICU admission could be baseline prognostic factors for death during treatment of adult patients with pulmonary TB in Korea.
KW - Korea
KW - Mortality
KW - Pulmonary
KW - Therapeutics
KW - Tuberculosis
UR - http://www.scopus.com/inward/record.url?scp=84929939240&partnerID=8YFLogxK
U2 - 10.3346/jkms.2014.29.9.1226
DO - 10.3346/jkms.2014.29.9.1226
M3 - Article
C2 - 25246740
AN - SCOPUS:84929939240
SN - 1011-8934
VL - 29
SP - 1226
EP - 1231
JO - Journal of Korean Medical Science
JF - Journal of Korean Medical Science
IS - 9
ER -