Rhodamine derivatives bearing the thiophene (1) and bisthiophene (2) groups are synthesized and their binding selectivity toward various metal ions was studied. The X-ray crystal structure of 1 was also reported. Probes 1 and 2 showed highly selective "Off-On" fluorescence changes with Hg 2+ among various metal ions. These selective changes were attributed to the spirolactam ring opening processes and subsequent hydrolysis. Probes 1 and 2 were sucessfully applied to the cell-imaging of Hg2+ using HeLa cells.
Bibliographical noteFunding Information:
This CRI work was supported by the National Research Foundation of Korea(NRF) grant funded by the Korea government(MEST) (No. 2012R1A3A2048814 ). Mass spectral data were obtained from the Korea Basic Science Institute (Daegu) on a Jeol JMS 700 high resolution mass spectrometer.
- Colorimetric sensor
- Fluorescent chemodosimeter
- Fluorescent chemosensor
- Mercury ion sensor