Rhodamine based fluorescent chemosensors for Hg 2+ and its biological application

Ji Young Choi; Wantae Kim; Juyoung Yoon

doi:10.5012/bkcs.2012.33.7.2359

Rhodamine based fluorescent chemosensors for Hg ²⁺ and its biological application

Ji Young Choi
, Wantae Kim
, Juyoung Yoon

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Two new chemosensors, rhodamine 6G derivative bearing hydroxyethyl group (1) and rhodamine base derivative bearing 15-crown-5 group (2) were synthesized and their sensing behaviors toward various metal ions were investigated by UV/Vis and fluorescence spectroscopies. Addition of Hg ²⁺ ion to a CH3CN solution of 1 and 2 gave visual color changes as well as fluorescent OFF-ON observations. Selectivity and sensitivity of 1 towards Hg ²⁺ are excellent enough to detect micromolar level of Hg ²⁺ ion, even in equeous media and biological sample (HeLa cell).

Original language	English
Pages (from-to)	2359-2364
Number of pages	6
Journal	Bulletin of the Korean Chemical Society
Volume	33
Issue number	7
DOIs	https://doi.org/10.5012/bkcs.2012.33.7.2359
State	Published - 20 Jul 2012

Keywords

Colorimetric sensor
Fluorescent sensor
Hg(II) sensor
Mercury ion sensor
Rhodamine

Access to Document

10.5012/bkcs.2012.33.7.2359

Cite this

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title = "Rhodamine based fluorescent chemosensors for Hg 2+ and its biological application",

abstract = "Two new chemosensors, rhodamine 6G derivative bearing hydroxyethyl group (1) and rhodamine base derivative bearing 15-crown-5 group (2) were synthesized and their sensing behaviors toward various metal ions were investigated by UV/Vis and fluorescence spectroscopies. Addition of Hg 2+ ion to a CH3CN solution of 1 and 2 gave visual color changes as well as fluorescent OFF-ON observations. Selectivity and sensitivity of 1 towards Hg 2+ are excellent enough to detect micromolar level of Hg 2+ ion, even in equeous media and biological sample (HeLa cell).",

keywords = "Colorimetric sensor, Fluorescent sensor, Hg(II) sensor, Mercury ion sensor, Rhodamine",

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AU - Choi, Ji Young

AU - Kim, Wantae

AU - Yoon, Juyoung

PY - 2012/7/20

Y1 - 2012/7/20

N2 - Two new chemosensors, rhodamine 6G derivative bearing hydroxyethyl group (1) and rhodamine base derivative bearing 15-crown-5 group (2) were synthesized and their sensing behaviors toward various metal ions were investigated by UV/Vis and fluorescence spectroscopies. Addition of Hg 2+ ion to a CH3CN solution of 1 and 2 gave visual color changes as well as fluorescent OFF-ON observations. Selectivity and sensitivity of 1 towards Hg 2+ are excellent enough to detect micromolar level of Hg 2+ ion, even in equeous media and biological sample (HeLa cell).

AB - Two new chemosensors, rhodamine 6G derivative bearing hydroxyethyl group (1) and rhodamine base derivative bearing 15-crown-5 group (2) were synthesized and their sensing behaviors toward various metal ions were investigated by UV/Vis and fluorescence spectroscopies. Addition of Hg 2+ ion to a CH3CN solution of 1 and 2 gave visual color changes as well as fluorescent OFF-ON observations. Selectivity and sensitivity of 1 towards Hg 2+ are excellent enough to detect micromolar level of Hg 2+ ion, even in equeous media and biological sample (HeLa cell).

KW - Colorimetric sensor

KW - Fluorescent sensor

KW - Hg(II) sensor

KW - Mercury ion sensor

KW - Rhodamine

UR - https://www.scopus.com/pages/publications/84864251841

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DO - 10.5012/bkcs.2012.33.7.2359

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VL - 33

SP - 2359

EP - 2364

JO - Bulletin of the Korean Chemical Society

JF - Bulletin of the Korean Chemical Society

IS - 7