Rhodamine based fluorescent chemosensors for Hg 2+ and its biological application

Ji Young Choi; Wantae Kim; Juyoung Yoon

doi:10.5012/bkcs.2012.33.7.2359

Rhodamine based fluorescent chemosensors for Hg ²⁺ and its biological application

Ji Young Choi, Wantae Kim, Juyoung Yoon

Department of Chemistry & Nanoscience

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Two new chemosensors, rhodamine 6G derivative bearing hydroxyethyl group (1) and rhodamine base derivative bearing 15-crown-5 group (2) were synthesized and their sensing behaviors toward various metal ions were investigated by UV/Vis and fluorescence spectroscopies. Addition of Hg ²⁺ ion to a CH3CN solution of 1 and 2 gave visual color changes as well as fluorescent OFF-ON observations. Selectivity and sensitivity of 1 towards Hg ²⁺ are excellent enough to detect micromolar level of Hg ²⁺ ion, even in equeous media and biological sample (HeLa cell).

Original language	English
Pages (from-to)	2359-2364
Number of pages	6
Journal	Bulletin of the Korean Chemical Society
Volume	33
Issue number	7
DOIs	https://doi.org/10.5012/bkcs.2012.33.7.2359
State	Published - 20 Jul 2012

Keywords

Colorimetric sensor
Fluorescent sensor
Hg(II) sensor
Mercury ion sensor
Rhodamine

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10.5012/bkcs.2012.33.7.2359

Cite this

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title = "Rhodamine based fluorescent chemosensors for Hg 2+ and its biological application",

abstract = "Two new chemosensors, rhodamine 6G derivative bearing hydroxyethyl group (1) and rhodamine base derivative bearing 15-crown-5 group (2) were synthesized and their sensing behaviors toward various metal ions were investigated by UV/Vis and fluorescence spectroscopies. Addition of Hg 2+ ion to a CH3CN solution of 1 and 2 gave visual color changes as well as fluorescent OFF-ON observations. Selectivity and sensitivity of 1 towards Hg 2+ are excellent enough to detect micromolar level of Hg 2+ ion, even in equeous media and biological sample (HeLa cell).",

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AU - Kim, Wantae

AU - Yoon, Juyoung

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AB - Two new chemosensors, rhodamine 6G derivative bearing hydroxyethyl group (1) and rhodamine base derivative bearing 15-crown-5 group (2) were synthesized and their sensing behaviors toward various metal ions were investigated by UV/Vis and fluorescence spectroscopies. Addition of Hg 2+ ion to a CH3CN solution of 1 and 2 gave visual color changes as well as fluorescent OFF-ON observations. Selectivity and sensitivity of 1 towards Hg 2+ are excellent enough to detect micromolar level of Hg 2+ ion, even in equeous media and biological sample (HeLa cell).

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KW - Fluorescent sensor

KW - Hg(II) sensor

KW - Mercury ion sensor

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