TY - JOUR
T1 - repeatability and reproducibility of tear meniscus evaluations using two different spectral domain-optical coherence tomography
AU - Kim, Jin Ha
AU - Choi, Kyu Ryong
AU - Jun, Roo Min
AU - Han, Kyung Eun
N1 - Funding Information:
* This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No. NRF-2017R1C1B1011577).
Publisher Copyright:
©2019 The Korean Ophthalmological Society
PY - 2019
Y1 - 2019
N2 - Purpose: To evaluate the repeatability and reproducibility of inferior tear meniscus measurements using two different spectral domain-optical coherence tomography (OCT), and to compare the inter-device agreements between these devices. Methods: Two examiners evaluated the tear meniscus depth (TMD) and tear meniscus height (TMH) of 20 eyes in 20 normal subjects using Cirrus OCT and Spectralis OCT with the examiners calculating the TMD and TMH. We analyzed intra-examiner repeatability, inter-examiner reproducibility, and inter-device agreement. Results: The average TMD measurements using the Cirrus OCT and Spectralis OCT devices were 151.25 ± 41.53 μm and 139.10 ± 40.56 μm by examiner 1, respectively, and 152.03 ± 42.77 μm and 138.35 ± 39.70 μm by examiner 2, respectively. The TMHs were 291.90 ± 100.19 μm and 245.43 ± 66.44 μm by examiner 1, respectively, and 288.25 ± 98.72 μm and 244.23 ± 60.69 μm by examiner 2, respectively. The TMDs and TMHs measured using these OCT devices were not statistically significant for intra-examiner and inter-examiner measurements (all, p > 0.05). These devices showed high repeatability (intraclass correlation coefficient ≥ 0.991) for intra-examiner TMD and TMH measurements and the inter-examiner coefficient of variation ranged from 2.04% to 4.32%. The 95% limits of agreement between the two devices were -66.13 to 91.95 μm for TMD and -127.18 to 217.68 μm for TMH. Conclusions: Both OCT devices are useful for conducting inferior tear meniscus measurements. The inter-device agreement was poor, and the devices were not interchangeable.
AB - Purpose: To evaluate the repeatability and reproducibility of inferior tear meniscus measurements using two different spectral domain-optical coherence tomography (OCT), and to compare the inter-device agreements between these devices. Methods: Two examiners evaluated the tear meniscus depth (TMD) and tear meniscus height (TMH) of 20 eyes in 20 normal subjects using Cirrus OCT and Spectralis OCT with the examiners calculating the TMD and TMH. We analyzed intra-examiner repeatability, inter-examiner reproducibility, and inter-device agreement. Results: The average TMD measurements using the Cirrus OCT and Spectralis OCT devices were 151.25 ± 41.53 μm and 139.10 ± 40.56 μm by examiner 1, respectively, and 152.03 ± 42.77 μm and 138.35 ± 39.70 μm by examiner 2, respectively. The TMHs were 291.90 ± 100.19 μm and 245.43 ± 66.44 μm by examiner 1, respectively, and 288.25 ± 98.72 μm and 244.23 ± 60.69 μm by examiner 2, respectively. The TMDs and TMHs measured using these OCT devices were not statistically significant for intra-examiner and inter-examiner measurements (all, p > 0.05). These devices showed high repeatability (intraclass correlation coefficient ≥ 0.991) for intra-examiner TMD and TMH measurements and the inter-examiner coefficient of variation ranged from 2.04% to 4.32%. The 95% limits of agreement between the two devices were -66.13 to 91.95 μm for TMD and -127.18 to 217.68 μm for TMH. Conclusions: Both OCT devices are useful for conducting inferior tear meniscus measurements. The inter-device agreement was poor, and the devices were not interchangeable.
KW - Cirrus optical coherence tomography
KW - Spectralis optical coherence tomography
KW - Tear meniscus depth
KW - Tear meniscus height
UR - http://www.scopus.com/inward/record.url?scp=85076811820&partnerID=8YFLogxK
U2 - 10.3341/jkos.2019.60.10.929
DO - 10.3341/jkos.2019.60.10.929
M3 - Article
AN - SCOPUS:85076811820
VL - 60
SP - 929
EP - 934
JO - Journal of Korean Ophthalmological Society
JF - Journal of Korean Ophthalmological Society
SN - 0378-6471
IS - 10
ER -