Relation between serum folate status and blood mercury concentrations in pregnant women

  • Hyesook Kim
  • , Ki Nam Kim
  • , Ji Yun Hwang
  • , Eun Hee Ha
  • , Hyesook Park
  • , Mina Ha
  • , Yangho Kim
  • , Yun Chul Hong
  • , Namsoo Chang

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Objective: To evaluate the relation between maternal serum folate status and blood mercury in pregnant Korean women. Methods: The nutritional status of folate and the blood mercury concentration were measured in pregnant Korean women who participated in a multicenter prospective study from 2006 through 2011. We analyzed existing blood mercury data based on serum folate status at two gestational time points (mid and late pregnancy, n = 1105 and 841, respectively). Results: Serum folate concentrations in pregnant women were negatively associated with blood mercury concentrations at mid and late pregnancy (P trend = 0.012 and 0.002, respectively). A general linear model developed after adjusting for covariates indicated a significant negative association between the two at mid and late pregnancy. Conclusion: We found a negative association between serum folate and blood mercury concentrations in pregnant Korean women.

Original languageEnglish
Pages (from-to)514-518
Number of pages5
JournalNutrition
Volume29
Issue number3
DOIs
StatePublished - Mar 2013

Bibliographical note

Funding Information:
This study was supported by the Mothers and Children's Environmental Health (MOCEH) Project of the Ministry of Environment , Republic of Korea.

Keywords

  • Folate intake
  • Mercury
  • Pregnant women
  • Serum folate

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