Regiospecific Conversion of Lipids and Fatty Acids through Enzymatic Cascade Reactions

Young Joo Yeon; Jin Byung Park

doi:10.1016/B978-0-12-813167-1.00007-4

Regiospecific Conversion of Lipids and Fatty Acids through Enzymatic Cascade Reactions

Young Joo Yeon, Jin Byung Park

Department of Food Science & Biotechnology

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

8 Scopus citations

Abstract

Biosynthesis of oleochemicals from lipids and fatty acids draws large attention due to growing interest in natural products and greener processes. Recent developments in biotransformation and biocatalysis based on synthetic biology, metabolic engineering, and enzyme engineering enable us to enhance the quality as well as the spectrum of oleochemicals obtainable from biomass. This chapter describes emerging ideas and cutting-edge technologies to produce high-value oleochemicals from renewable lipids and fatty acids. Especially, the enzyme-based multistep biotransformation of long-chain fatty acids into medium-chain ω-hydroxycarboxylic, α,ω-dicarboxylic, and ω-aminocarboxylic acids are focused on.

Original language	English
Title of host publication	Lipid Modification by Enzymes and Engineered Microbes
Publisher	Elsevier
Pages	139-155
Number of pages	17
ISBN (Electronic)	9780128131688
ISBN (Print)	9780128131671
DOIs	https://doi.org/10.1016/B978-0-12-813167-1.00007-4
State	Published - 20 Mar 2018

Bibliographical note

Publisher Copyright:
© 2018 Elsevier Inc. All rights reserved.

Keywords

Baeyer-Villiger monooxygenases
Enzymatic cascade reaction
Fatty acid biotransformation
α,ω-dicarboxylic acids
ω-aminocarboxylic acids
ω-hydroxycarboxylic acids

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10.1016/B978-0-12-813167-1.00007-4

Cite this

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title = "Regiospecific Conversion of Lipids and Fatty Acids through Enzymatic Cascade Reactions",

abstract = "Biosynthesis of oleochemicals from lipids and fatty acids draws large attention due to growing interest in natural products and greener processes. Recent developments in biotransformation and biocatalysis based on synthetic biology, metabolic engineering, and enzyme engineering enable us to enhance the quality as well as the spectrum of oleochemicals obtainable from biomass. This chapter describes emerging ideas and cutting-edge technologies to produce high-value oleochemicals from renewable lipids and fatty acids. Especially, the enzyme-based multistep biotransformation of long-chain fatty acids into medium-chain ω-hydroxycarboxylic, α,ω-dicarboxylic, and ω-aminocarboxylic acids are focused on.",

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AU - Park, Jin Byung

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AB - Biosynthesis of oleochemicals from lipids and fatty acids draws large attention due to growing interest in natural products and greener processes. Recent developments in biotransformation and biocatalysis based on synthetic biology, metabolic engineering, and enzyme engineering enable us to enhance the quality as well as the spectrum of oleochemicals obtainable from biomass. This chapter describes emerging ideas and cutting-edge technologies to produce high-value oleochemicals from renewable lipids and fatty acids. Especially, the enzyme-based multistep biotransformation of long-chain fatty acids into medium-chain ω-hydroxycarboxylic, α,ω-dicarboxylic, and ω-aminocarboxylic acids are focused on.

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KW - Fatty acid biotransformation

KW - α,ω-dicarboxylic acids

KW - ω-aminocarboxylic acids

KW - ω-hydroxycarboxylic acids

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M3 - Chapter

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BT - Lipid Modification by Enzymes and Engineered Microbes

PB - Elsevier

ER -

Regiospecific Conversion of Lipids and Fatty Acids through Enzymatic Cascade Reactions

Abstract

Bibliographical note

Keywords

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