Regiospecific Conversion of Lipids and Fatty Acids through Enzymatic Cascade Reactions

Young Joo Yeon, Jin Byung Park

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

5 Scopus citations

Abstract

Biosynthesis of oleochemicals from lipids and fatty acids draws large attention due to growing interest in natural products and greener processes. Recent developments in biotransformation and biocatalysis based on synthetic biology, metabolic engineering, and enzyme engineering enable us to enhance the quality as well as the spectrum of oleochemicals obtainable from biomass. This chapter describes emerging ideas and cutting-edge technologies to produce high-value oleochemicals from renewable lipids and fatty acids. Especially, the enzyme-based multistep biotransformation of long-chain fatty acids into medium-chain ω-hydroxycarboxylic, α,ω-dicarboxylic, and ω-aminocarboxylic acids are focused on.

Original languageEnglish
Title of host publicationLipid Modification by Enzymes and Engineered Microbes
PublisherElsevier
Pages139-155
Number of pages17
ISBN (Electronic)9780128131688
ISBN (Print)9780128131671
DOIs
StatePublished - 20 Mar 2018

Keywords

  • Baeyer-Villiger monooxygenases
  • Enzymatic cascade reaction
  • Fatty acid biotransformation
  • α,ω-dicarboxylic acids
  • ω-aminocarboxylic acids
  • ω-hydroxycarboxylic acids

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