@article{2dd7408cd5604579a2686db82afaa041,
title = "Redox-responsive nanoparticles self-assembled from porphyrin-betulinic acid conjugates for chemo- and photodynamic therapy",
abstract = "The redox-responsive nanoparticle (NanoP-ss-BA) is designed by linking the porphyrin derivative (P) to the naturally occurring betulinic acid (BA) through a disulphide bond. A GSH triggered disassembly of NanoP-ss-BA effectively promotes a singlet oxygen (1O2) production, but also releases lipophilic anticancer drug, BA in situ. Beside this, high phototoxicity of NanoP-ss-BA serves it as a good candidate for photodynamic therapy (PDT).",
keywords = "Photodynamic therapy, Redox-responsive, ROS, Self-assembled nanoparticles, Tumour targeting",
author = "Zulal {\"O}zdemir and Mengyao Yang and Gyoungmi Kim and Uladzimir Bildziukevich and David {\v S}aman and Xingshu Li and Juyoung Yoon and Zden{\v e}k Wimmer",
note = "Funding Information: J.Y. thanks to the support from the National Research Foundation of Korea (NRF) funded by the Korean government ( MSIP ) (No. 2012R1A3A2048814 ). Z.{\"O}., U. B. and Z. W. thank for funds from MPO , grants No. FV10599 and FV30300 . Z.{\"O}. thanks the Czech Academy of Sciences grant (No. VAJVA-19-48 ) and University of Chemistry and Technology Prague, MOBI traineeship Programme 2019/2020 for support of her visit to the EWHA Womans University, Seoul. X.L. thanks the National Natural Science Foundation of China (Grant No. 22078066 ). M.Y. thanks the China Scholarship Council (CSC , No. 201904910820) . The authors thank Ms. Michala Jirsov{\'a} for her participation in the partial synthesis as a student. Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd",
year = "2021",
month = jun,
doi = "10.1016/j.dyepig.2021.109307",
language = "English",
volume = "190",
journal = "Dyes and Pigments",
issn = "0143-7208",
publisher = "Elsevier BV",
}