Recurrent meningococcal meningitis with complement 6 (C6) deficiency: A case report

Ji Yun Bae, Ahrong Ham, Hee Jung Choi, Chung Jong Kim

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3 Scopus citations


Rationale:Late complement deficiency increases susceptibility to meningococcal disease and recurrent infections. In Korea, 5 case reports have described meningococcal disease with complement deficiency. However, C6 deficiency has not been described previously.Patient concerns:A 21-year-old police trainee presented with recurrent meningococcal meningitis. He was housed in communal living quarters until 20 days before the initial symptom onset.Diagnosis:He was diagnosed with meningococcal meningitis with C6 deficiency.Interventions:He was treated with intravenous ceftriaxone. An additional dose of quadrivalent meningococcal conjugate vaccine was administered after discharge.Outcomes:He was discharged without complications.Lessons:Screening for complement deficiency is necessary in patients with a history of recurrent meningococcal infections to provide appropriate care and prevent recurrent infections.

Original languageEnglish
Pages (from-to)E20362
JournalMedicine (United States)
Issue number21
StatePublished - 22 May 2020

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  • C6 deficiency
  • Neisseria meningitidis
  • complement deficiency
  • meningococcal meningitis


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