Recent progress on photodynamic therapy and photothermal therapy

Heejeong Kim, Mengyao Yang, Nahyun Kwon, Moonyeon Cho, Jingjing Han, Rui Wang, Sujie Qi, Haidong Li, Van Nghia Nguyen, Xingshu Li, Hong Bo Cheng, Juyoung Yoon

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Noninvasive treatments for terminal cancer patients constitute a new trend in tumor treatment. Therefore, phototherapy, including photodynamic therapy (PDT) and photothermal therapy (PTT), has attracted considerable interest. Light and a photosensitizer (PS) are employed in both treatment methods. For PDT, the PS generates reactive oxygen species (ROS) when exposed to light, whereas for PTT, the PS generates heat. In this regard, the systematic design of new PSs has become an active area of phototherapy research in an effort to solve the problems associated with conventional PSs. In the past decade, activatable and heavy-atom-free PSs have become significant research areas. Therefore, we discuss our recent contributions to the PDT and PTT in this account.

Original languageEnglish
Pages (from-to)236-255
Number of pages20
JournalBulletin of the Korean Chemical Society
Volume44
Issue number3
DOIs
StatePublished - Mar 2023

Bibliographical note

Publisher Copyright:
© 2022 Korean Chemical Society, Seoul & Wiley-VCH GmbH.

Keywords

  • photodynamic therapy
  • photosensitizers
  • phototherapy
  • photothermal therapy
  • theranostics

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