Abstract
Metal ions are of significance in various pathological and physiological processes. As such, it is crucial to monitor their levels in organisms. Two-photon (TP) and near-infrared (NIR) fluorescence imaging has been utilized to monitor metal ions because of minimal background interference, deeper tissue depth penetration, lower tissue self-absorption, and reduced photodamage. In this review, we briefly summarize recent progress from 2020 to 2022 of TP/NIR organic fluorescent probes and inorganic sensors in the detection of metal ions. Additionally, we present an outlook for the development of TP/NIR probes for bio-imaging, diagnosis of diseases, imaging-guided therapy, and activatable phototherapy.
Original language | English |
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Article number | 102321 |
Journal | Current Opinion in Chemical Biology |
Volume | 75 |
DOIs | |
State | Published - Aug 2023 |
Keywords
- Fluorescence imaging
- Fluorescent probes
- Metal ions
- Near-infrared
- Two-photon