Recent advances in the use of photochromic dyes for photocontrol in biomedicine

Hongbo Cheng, Juyoung Yoon, He Tian

Research output: Contribution to journalReview articlepeer-review

83 Scopus citations

Abstract

Light can play important roles in controlling biochemical processes. Owing to their high spatiotemporal resolution and non-invasive nature, light can be utilized as smart triggers to mediate the biological activities of substances. In this review, we summarize important photochromic dye based photoswitchable substances that have been developed in recent years. Additionally, the basic principles involved in the design of the photochromic biomaterials, and insights into how to expand applications of these light activated agents and the key challenges that need to be considered are discussed.

Original languageEnglish
Pages (from-to)66-84
Number of pages19
JournalCoordination Chemistry Reviews
Volume372
DOIs
StatePublished - 1 Oct 2018

Bibliographical note

Funding Information:
J. Y. acknowledges a grant from the National Creative Research Initiative programs of the National Research Foundation of Korea (NRF) funded by the Korean government (MSIP) (No. 2012R1A3A2048814 ). H. Cheng acknowledges funding from the National Natural Science Foundation of China ( 21502195 ).

Publisher Copyright:
© 2018 Elsevier B.V.

Keywords

  • Bioimaging
  • Biomedicine
  • Molecular recognition
  • Photochromic dyes
  • Photoreversible

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