Recent advances in quantum nanophotonics: Plexcitonic and vibro-polaritonic strong coupling and its biomedical and chemical applications

Yangkyu Kim, Aleksandr Barulin, Sangwon Kim, Luke P. Lee, Inki Kim

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


The fundamental understanding of molecular quantum electrodynamics via the strong light-matter interactions between a nanophotonic cavity and quantum emitters opens various applications in quantum biology, biophysics, and chemistry. However, considerable obstacles to obtaining a clear understanding of coupling mechanisms via reliable experimental quantifications remain to be resolved before this field can truly blossom toward practical applications in quantitative life science and photochemistry. Here, we provide recent advancements of state-of-the-art demonstrations in plexcitonic and vibro-polaritonic strong couplings and their applications. We highlight recent studies on various strong coupling systems for altering chemical reaction landscapes. Then, we discuss reports dedicated to the utilization of strong coupling methods for biomolecular sensing, protein functioning studies, and the generation of hybrid light-matter states inside living cells. The strong coupling regime provides a tool for investigating and altering coherent quantum processes in natural biological processes. We also provide an overview of new findings and future avenues of quantum biology and biochemistry.

Original languageEnglish
Pages (from-to)413-439
Number of pages27
Issue number3
StatePublished - 1 Feb 2023

Bibliographical note

Funding Information:
Research funding: This work was financially supported by National Research Foundation (NRF) grants (NRF-2020R1A5A1019649, NRF-2022M3C1A3081312) funded by the Ministry of Science and ICT (MSIT) of the Korean government. I.K. acknowledges the NRF Sejong Science fellowship (NRF-2021R1C1C2004291) funded by the MSIT of the Korean government.

Publisher Copyright:
© 2022 the author(s), published by De Gruyter, Berlin/Boston.


  • chemical reaction
  • plexcitons
  • quantum biological process
  • strong coupling
  • vibro-polaritonic strong coupling


Dive into the research topics of 'Recent advances in quantum nanophotonics: Plexcitonic and vibro-polaritonic strong coupling and its biomedical and chemical applications'. Together they form a unique fingerprint.

Cite this