TY - JOUR
T1 - Recent advances in biocompatible semiconductor nanocrystals for immunobiological applications
AU - Nanda, Sitansu Sekhar
AU - Kim, Min Jik
AU - Kim, Kwangmeyung
AU - Papaefthymiou, Georgia C.
AU - Selvan, Subramanian Tamil
AU - Yi, Dong Kee
N1 - Funding Information:
This work was supported by 2016 Research Fund of Myongji University in Korea .
Publisher Copyright:
© 2017 Elsevier B.V.
PY - 2017/11/1
Y1 - 2017/11/1
N2 - Quantum confinement in inorganic semiconductor nanocrystals produces brightly luminescent nanoparticles endowed with unique photo-physical properties, such as tunable optical properties. These have found widespread applications in nanotechnology. The ability to render such nanostructures biocompatible, while maintaining their tunable radiation in the visible range of the electromagnetic spectrum, renders them appropriate for bio-applications. Promising in vitro and in vivo diagnostic applications have been demonstrated, such as fluorescence-based detection of biological interactions, single molecule tracking, multiplexing and immunoassaying. In particular, these fluorescent inorganic semiconductor nanocrystals, generally known as quantum dots, have the potential of remarkable immunobiological applications. This review focuses on the current status of biocompatible quantum dots and their applications in immunobiology − immunosensing, immunofluorescent imaging and immunotherapy.
AB - Quantum confinement in inorganic semiconductor nanocrystals produces brightly luminescent nanoparticles endowed with unique photo-physical properties, such as tunable optical properties. These have found widespread applications in nanotechnology. The ability to render such nanostructures biocompatible, while maintaining their tunable radiation in the visible range of the electromagnetic spectrum, renders them appropriate for bio-applications. Promising in vitro and in vivo diagnostic applications have been demonstrated, such as fluorescence-based detection of biological interactions, single molecule tracking, multiplexing and immunoassaying. In particular, these fluorescent inorganic semiconductor nanocrystals, generally known as quantum dots, have the potential of remarkable immunobiological applications. This review focuses on the current status of biocompatible quantum dots and their applications in immunobiology − immunosensing, immunofluorescent imaging and immunotherapy.
KW - Immunoassay
KW - Immunofluorescent imaging
KW - Immunosensor
KW - Immunotherapy
KW - Quantum dots
UR - http://www.scopus.com/inward/record.url?scp=85028562090&partnerID=8YFLogxK
U2 - 10.1016/j.colsurfb.2017.08.026
DO - 10.1016/j.colsurfb.2017.08.026
M3 - Review article
C2 - 28865361
AN - SCOPUS:85028562090
SN - 0927-7765
VL - 159
SP - 644
EP - 654
JO - Colloids and Surfaces B: Biointerfaces
JF - Colloids and Surfaces B: Biointerfaces
ER -