Abstract
Quinone oxidoreductase (NQO1) plays a key role in the cellular antioxidant defense by detoxifying quinine derivatives. Case-control association study of the possible relationship between the NQO1 gene polymorphism and mood disorders (patients with major depressive disorder, n = 61; patients with bipolar I disorder, n = 80; control, n = 106) was carried out using PCR-based techniques. These preliminary results showed that the NQO1 gene polymorphism was not related to a susceptibility to mood disorders.
Original language | English |
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Pages (from-to) | 83-86 |
Number of pages | 4 |
Journal | Psychiatry Research |
Volume | 153 |
Issue number | 1 |
DOIs | |
State | Published - 30 Sep 2007 |
Bibliographical note
Funding Information:This study was supported by a grant (KRF-2004-003-E00145) from the Korea Research Foundation. The authors express their sincere gratitude to all the patients who participated in the study.
Keywords
- Mood disorder
- NQO1 gene
- Polymorphism