Quantitative screening for endocrine-disrupting bisphenol A in consumer and household products using NanoAptamer assay

Hyun Jeong Lim; Eun Hee Lee; Sang Don Lee; Yeomin Yoon; Ahjeong Son

doi:10.1016/j.chemosphere.2018.07.125

Quantitative screening for endocrine-disrupting bisphenol A in consumer and household products using NanoAptamer assay

Hyun Jeong Lim, Eun Hee Lee, Sang Don Lee, Yeomin Yoon, Ahjeong Son

Department of Environmental Science & Engineering

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

The NanoAptamer assay is a bisphenol A (BPA) quantification method that uses magnetic beads, quantum dot nanoparticles, and a BPA-specific aptamer. In this study, screening of various consumer and household products for BPA was demonstrated utilizing the NanoAptamer assay. First, the experimental conditions suitable for BPA detection using the NanoAptamer assay were examined in terms of incubation time, temperature, and buffer composition. The range of BPA quantification via the NanoAptamer assay was determined to be 0.005–1000 ng/mL of BPA. The selectivity was confirmed by detecting BPA in an analog mixture containing bisphenol S and bisphenol F. Finally, a leaching experiment using 20 consumer and household products classified into 4 categories was performed to demonstrate the capability of the NanoAptamer assay for BPA detection. The experiment was validated by high-performance liquid chromatography analysis (correlation coefficient, r = 0.99).

Original language	English
Pages (from-to)	72-80
Number of pages	9
Journal	Chemosphere
Volume	211
DOIs	https://doi.org/10.1016/j.chemosphere.2018.07.125
State	Published - Nov 2018

Bibliographical note

Publisher Copyright:
© 2018 Elsevier Ltd

Keywords

Aptamer
Aptasensor
Bisphenol A
Endocrine disrupting chemicals
Quantum dots

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.chemosphere.2018.07.125

Cite this

@article{a45e4b72aabf469aabf0f6faf6e62094,

title = "Quantitative screening for endocrine-disrupting bisphenol A in consumer and household products using NanoAptamer assay",

abstract = "The NanoAptamer assay is a bisphenol A (BPA) quantification method that uses magnetic beads, quantum dot nanoparticles, and a BPA-specific aptamer. In this study, screening of various consumer and household products for BPA was demonstrated utilizing the NanoAptamer assay. First, the experimental conditions suitable for BPA detection using the NanoAptamer assay were examined in terms of incubation time, temperature, and buffer composition. The range of BPA quantification via the NanoAptamer assay was determined to be 0.005–1000 ng/mL of BPA. The selectivity was confirmed by detecting BPA in an analog mixture containing bisphenol S and bisphenol F. Finally, a leaching experiment using 20 consumer and household products classified into 4 categories was performed to demonstrate the capability of the NanoAptamer assay for BPA detection. The experiment was validated by high-performance liquid chromatography analysis (correlation coefficient, r = 0.99).",

keywords = "Aptamer, Aptasensor, Bisphenol A, Endocrine disrupting chemicals, Quantum dots",

author = "Lim, {Hyun Jeong} and Lee, {Eun Hee} and Lee, {Sang Don} and Yeomin Yoon and Ahjeong Son",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Ltd",

year = "2018",

month = nov,

doi = "10.1016/j.chemosphere.2018.07.125",

language = "English",

volume = "211",

pages = "72--80",

journal = "Chemosphere",

issn = "0045-6535",

publisher = "Elsevier Ltd.",

}

TY - JOUR

T1 - Quantitative screening for endocrine-disrupting bisphenol A in consumer and household products using NanoAptamer assay

AU - Lim, Hyun Jeong

AU - Lee, Eun Hee

AU - Lee, Sang Don

AU - Yoon, Yeomin

AU - Son, Ahjeong

PY - 2018/11

Y1 - 2018/11

N2 - The NanoAptamer assay is a bisphenol A (BPA) quantification method that uses magnetic beads, quantum dot nanoparticles, and a BPA-specific aptamer. In this study, screening of various consumer and household products for BPA was demonstrated utilizing the NanoAptamer assay. First, the experimental conditions suitable for BPA detection using the NanoAptamer assay were examined in terms of incubation time, temperature, and buffer composition. The range of BPA quantification via the NanoAptamer assay was determined to be 0.005–1000 ng/mL of BPA. The selectivity was confirmed by detecting BPA in an analog mixture containing bisphenol S and bisphenol F. Finally, a leaching experiment using 20 consumer and household products classified into 4 categories was performed to demonstrate the capability of the NanoAptamer assay for BPA detection. The experiment was validated by high-performance liquid chromatography analysis (correlation coefficient, r = 0.99).

AB - The NanoAptamer assay is a bisphenol A (BPA) quantification method that uses magnetic beads, quantum dot nanoparticles, and a BPA-specific aptamer. In this study, screening of various consumer and household products for BPA was demonstrated utilizing the NanoAptamer assay. First, the experimental conditions suitable for BPA detection using the NanoAptamer assay were examined in terms of incubation time, temperature, and buffer composition. The range of BPA quantification via the NanoAptamer assay was determined to be 0.005–1000 ng/mL of BPA. The selectivity was confirmed by detecting BPA in an analog mixture containing bisphenol S and bisphenol F. Finally, a leaching experiment using 20 consumer and household products classified into 4 categories was performed to demonstrate the capability of the NanoAptamer assay for BPA detection. The experiment was validated by high-performance liquid chromatography analysis (correlation coefficient, r = 0.99).

KW - Aptamer

KW - Aptasensor

KW - Bisphenol A

KW - Endocrine disrupting chemicals

KW - Quantum dots

UR - http://www.scopus.com/inward/record.url?scp=85053187596&partnerID=8YFLogxK

U2 - 10.1016/j.chemosphere.2018.07.125

DO - 10.1016/j.chemosphere.2018.07.125

M3 - Article

C2 - 30071438

AN - SCOPUS:85053187596

SN - 0045-6535

VL - 211

SP - 72

EP - 80

JO - Chemosphere

JF - Chemosphere

ER -

Quantitative screening for endocrine-disrupting bisphenol A in consumer and household products using NanoAptamer assay

Abstract

Bibliographical note

Keywords

UN SDGs

Access to Document

Fingerprint

Cite this