Quantitative investigations on thermal response of adipose tissue to focused ultrasonic energy

Hanjae Pyo, Suhyun Park, Jae Hyun Jung, Sung Min Kim, Hyun Wook Kang

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2 Scopus citations


Thermal responses of adipose tissue to high intensity focused ultrasound (HIFU) were quantitatively evaluated for effective clinical lipolysis. A single-element HIFU transducer (4MHz and 4.5mm focal depth) was used in a linear motion to thermally treat the tissue at various acoustic energy densities and treatment gaps. Both interstitial temperature rise and denatured lesions increased with the energy density (up to 21.1 + 1.9K and 0.40 + 0.15mm2). No thermal overlapping was observed due to selective application of the ultrasonic beams. The optimization of noninvasive HIFU treatment parameters may ensure clinical outcomes of HIFU-assisted lipolysis in terms of efficacy and safety.

Original languageEnglish
Article number07JF03
JournalJapanese Journal of Applied Physics
Issue number7
StatePublished - Jul 2017

Bibliographical note

Funding Information:
This research was supported by a grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health and Welfare, Republic of Korea (Grant Number HI16C1017).

Publisher Copyright:
© 2017 The Japan Society of Applied Physics.


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