Quantitative electroencephalographic (qEEG) correlates of craving during virtual reality therapy in alcohol-dependent patients

Sang Hoon Lee; Doug Hyun Han; Seman Oh; In Kyoon Lyoo; Young Sik Lee; Perry F. Renshaw; Scott E. Lukas

doi:10.1016/j.pbb.2008.08.014

Quantitative electroencephalographic (qEEG) correlates of craving during virtual reality therapy in alcohol-dependent patients

Sang Hoon Lee, Doug Hyun Han, Seman Oh, In Kyoon Lyoo, Young Sik Lee, Perry F. Renshaw, Scott E. Lukas

Department of Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

Abstract

Virtual reality (VR) is an evolving technology that is being applied to treat a wide range of medical and psychiatric diseases. A virtual reality therapy (VRT) with multisensory stimulation has been applied to patients with alcohol dependence (ADP). We hypothesized that the VRTP for alcohol dependence would reduce the craving for alcohol and increase alpha wave activity in frontal areas of individuals with ADP. Twenty ADP and eighteen ADP were exposed to a series of 10 VRTP sessions (VRTP-ADP) and cognitive behavioral therapy (nVRTP-ADP), respectively. Fifteen healthy controls were exposed to VRTP for comparing the changes of craving and EEG during all three phases of VRTP. The VRTP-ADP exhibited a greater decrease in craving after the 10th VRTP session, when compared to the nVRTP-ADP. Compared to the healthy control subjects, VRTP-ADP group showed higher magnitude of the change in craving throughout VRTP sessions. These results suggest that VRTP may be useful as an adjunct to treating alcohol dependence but may also serve as an evaluation tool to identify high-risk patients. Crown

Original language	English
Pages (from-to)	393-397
Number of pages	5
Journal	Pharmacology Biochemistry and Behavior
Volume	91
Issue number	3
DOIs	https://doi.org/10.1016/j.pbb.2008.08.014
State	Published - Jan 2009

Bibliographical note

Funding Information:
We are thankful for the technical help of Blue Media Technology Co., Ltd., Korea. This research was supported by a Research Grant for alcohol treatment by Grants from Seo Cheon foundation 2006, Korea and NIDA Grants DA015116 and DA003H3.

Keywords

Alcohol dependence
Craving
EEG
Frontal cortex
Virtual reality

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10.1016/j.pbb.2008.08.014

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title = "Quantitative electroencephalographic (qEEG) correlates of craving during virtual reality therapy in alcohol-dependent patients",

abstract = "Virtual reality (VR) is an evolving technology that is being applied to treat a wide range of medical and psychiatric diseases. A virtual reality therapy (VRT) with multisensory stimulation has been applied to patients with alcohol dependence (ADP). We hypothesized that the VRTP for alcohol dependence would reduce the craving for alcohol and increase alpha wave activity in frontal areas of individuals with ADP. Twenty ADP and eighteen ADP were exposed to a series of 10 VRTP sessions (VRTP-ADP) and cognitive behavioral therapy (nVRTP-ADP), respectively. Fifteen healthy controls were exposed to VRTP for comparing the changes of craving and EEG during all three phases of VRTP. The VRTP-ADP exhibited a greater decrease in craving after the 10th VRTP session, when compared to the nVRTP-ADP. Compared to the healthy control subjects, VRTP-ADP group showed higher magnitude of the change in craving throughout VRTP sessions. These results suggest that VRTP may be useful as an adjunct to treating alcohol dependence but may also serve as an evaluation tool to identify high-risk patients. Crown",

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AU - Lee, Young Sik

AU - Renshaw, Perry F.

AU - Lukas, Scott E.

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Quantitative electroencephalographic (qEEG) correlates of craving during virtual reality therapy in alcohol-dependent patients

Abstract

Bibliographical note

Keywords

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