Quantification of inhibitory impact of heavy metals on the growth of Escherichia coli

Kyung Suk Cho, Yeun Koo So, Young Kim Ji, Wook Ryu Hee

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The quantification of the toxicological effects of the heavy metals such as Cu, Cd, Cr, Hg, and Zn on the growth of Escherichia coli was performed, and the variations of toxicities with exposure time were evaluated in adaptation procedure. The characteristics of growth inhibition on Escherichia coli by heavy metals were different with metal species, and critical concentration of each metal, which inhibited cell growth completely, were Cu of 3.5 mM, Zn of 2.5 mM, Cd of 1.5 mM, Cr of 1.2 mM, and Hg of 0.12 mM, respectively. The tolerance of E. coli against heavy metals, based on EC50 values, increased in order of Cu > Zn > Cr > Cd > Hg. The slopes obtained from the relationship between EC50 values and expose time corresponds to adaptability of test organisms to the toxicants. The adaptability of test organisms to the toxicants was much higher at higher slope values. Adaptability of E. coli on heavy metals increased in order to Zn > Cd > Cu ≫ Cr > Hg.

Original languageEnglish
Pages (from-to)341-346
Number of pages6
JournalKorean Journal of Microbiology and Biotechnology
Volume32
Issue number4
StatePublished - Dec 2004

Keywords

  • EC
  • Escherichia coli
  • Growth inhibition
  • Heavy metal
  • Toxicity

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