Quantification of Amyloid fibrilization by simultaneous dual mode detection with optical scattering image and dielectric relaxation spectroscopy

Yeonho Choi; Luke P. Lee

Quantification of Amyloid fibrilization by simultaneous dual mode detection with optical scattering image and dielectric relaxation spectroscopy

Department of Chemistry & Nanoscience

Research output: Contribution to conference › Paper › peer-review

Abstract

We demonstrate the dual mode quantification method of Amyloid-β fibrilization using dark-field optical imaging and dielectric relaxation spectroscopy. Optically transparent sub-micron gap microfluidic electrode is designed to observe the change of hydrodynamic radius during the process of Amyloid-β fibrilization and correlated the hydrodynamic radius via dual mode measurements.

Original language	English
Pages	342-344
Number of pages	3
State	Published - 2008
Event	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: 12 Oct 2008 → 16 Oct 2008

Conference

Conference	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country/Territory	United States
City	San Diego, CA
Period	12/10/08 → 16/10/08

Keywords

Amyloid-β
Dark-field image
Dielectric relaxation spectroscopy

Cite this

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title = "Quantification of Amyloid fibrilization by simultaneous dual mode detection with optical scattering image and dielectric relaxation spectroscopy",

abstract = "We demonstrate the dual mode quantification method of Amyloid-β fibrilization using dark-field optical imaging and dielectric relaxation spectroscopy. Optically transparent sub-micron gap microfluidic electrode is designed to observe the change of hydrodynamic radius during the process of Amyloid-β fibrilization and correlated the hydrodynamic radius via dual mode measurements.",

keywords = "Amyloid-β, Dark-field image, Dielectric relaxation spectroscopy",

author = "Yeonho Choi and Lee, {Luke P.}",

year = "2008",

language = "English",

pages = "342--344",

note = "12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 ; Conference date: 12-10-2008 Through 16-10-2008",

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Quantification of Amyloid fibrilization by simultaneous dual mode detection with optical scattering image and dielectric relaxation spectroscopy. / Choi, Yeonho; Lee, Luke P.
2008. 342-344 Paper presented at 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008, San Diego, CA, United States.

Research output: Contribution to conference › Paper › peer-review

TY - CONF

T1 - Quantification of Amyloid fibrilization by simultaneous dual mode detection with optical scattering image and dielectric relaxation spectroscopy

AU - Choi, Yeonho

AU - Lee, Luke P.

PY - 2008

Y1 - 2008

N2 - We demonstrate the dual mode quantification method of Amyloid-β fibrilization using dark-field optical imaging and dielectric relaxation spectroscopy. Optically transparent sub-micron gap microfluidic electrode is designed to observe the change of hydrodynamic radius during the process of Amyloid-β fibrilization and correlated the hydrodynamic radius via dual mode measurements.

AB - We demonstrate the dual mode quantification method of Amyloid-β fibrilization using dark-field optical imaging and dielectric relaxation spectroscopy. Optically transparent sub-micron gap microfluidic electrode is designed to observe the change of hydrodynamic radius during the process of Amyloid-β fibrilization and correlated the hydrodynamic radius via dual mode measurements.

KW - Amyloid-β

KW - Dark-field image

KW - Dielectric relaxation spectroscopy

UR - http://www.scopus.com/inward/record.url?scp=84902509317&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:84902509317

SP - 342

EP - 344

T2 - 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008

Y2 - 12 October 2008 through 16 October 2008

ER -

Quantification of Amyloid fibrilization by simultaneous dual mode detection with optical scattering image and dielectric relaxation spectroscopy

Abstract

Conference

Keywords

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Cite this