Protonolysis of a ruthenium-carbene bond and applications in olefin metathesis

Benjamin K. Keitz, Jean Bouffard, Guy Bertrand, Robert H. Grubbs

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The synthesis of a ruthenium complex containing an N-heterocylic carbene (NHC) and a mesoionic carbene (MIC) is described wherein addition of a Brønsted acid results in protonolysis of the Ru-MIC bond to generate an extremely active metathesis catalyst. Mechanistic studies implicated a rate-determining protonation step in the generation of the metathesis-active species. The activity of the NHC/MIC catalyst was found to exceed those of current commercial ruthenium catalysts.

Original languageEnglish
Pages (from-to)8498-8501
Number of pages4
JournalJournal of the American Chemical Society
Issue number22
StatePublished - 8 Jun 2011


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