Prospects of coupled iron-based nanostructures in preclinical antibacterial therapy

Jingjing Han, Shuang Zeng, Yahui Chen, Haidong Li, Juyoung Yoon

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Bacterial infections can threaten human health. Drug-resistant bacteria have become a challenge because of the excessive use of drugs. We summarize the current metallic antibacterial materials, especially Fe-based materials, for efficiently killing bacteria. The possible antibacterial mechanisms of metallic antibacterial agents are classified into interactions with bacterial proteins, iron metabolism, catalytic activity, and combinations of magnetic, photodynamic, and photothermal effects. This review will inspire the development of novel Fe-based antibacterial agents for clinical settings.

Original languageEnglish
Article number114672
JournalAdvanced Drug Delivery Reviews
StatePublished - Feb 2023

Bibliographical note

Funding Information:
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government(MSIT) (No. 2022R1A2C3005420). and the Fundamental Research Funds for the Central Universities (No. DUT22RC(3)025, H. Li).

Publisher Copyright:
© 2022 Elsevier B.V.


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