Primary chest wall sarcoma: Surgical outcomes and prognostic factors

Ilkun Park, Sumin Shin, Hong Kwan Kim, Yong Soo Choi, Jhingook Kim, Jae Ill Zo, Young Mog Shim, Jong Ho Cho

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Background: Primary chest wall sarcoma is a rare disease with limited reports of surgical resection. Methods: This retrospective review included 41 patients with primary chest wall sarcoma who underwent chest wall resection and reconstruction from 2001 to 2015. The clinical, histologic, and surgical variables were collected and analyzed by univariate and multivariate Cox regression analyses for overall survival (OS) and recurrence- free survival (RFS). Results: The OS rates at 5 and 10 years were 73% and 61%, respectively. The RFS rate at 10 years was 57.1%. Multivariate Cox regression analysis revealed old age (hazard ratio [HR], 5.16; 95% confidence interval [CI], 1.71-15.48) as a significant risk factor for death. A surgical resection margin distance of less than 1.5 cm (HR, 15.759; 95% CI, 1.78-139.46) and histologic grade III (HR, 28.36; 95% CI, 2.76-290.87) were independent risk factors for recurrence. Conclusion: Long-term OS and RFS after the surgical resection of primary chest wall sarcoma were clinically acceptable.

Original languageEnglish
Pages (from-to)360-367
Number of pages8
JournalKorean Journal of Thoracic and Cardiovascular Surgery
Volume52
Issue number5
DOIs
StatePublished - 2019

Keywords

  • Chest wall
  • Sarcoma
  • Undifferentiated pleomorphic sarcoma

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