Prevalence, risk factors and survival of lung cancer in the idiopathic pulmonary fibrosis

Kyung Jong Lee; Man Pyo Chung; Young Whan Kim; Jae Ho Lee; Kyu Sik Kim; Jeong Seon Ryu; Hong Lyeol Lee; Sung Woo Park; Choon Sik Park; Soo Tak Uh; Yong Chul Lee; Seoung Ju Park; Kwan Hyoung Kim; Young June Jeon; Won Il Choi; Yong Bum Park; Dong Soon Kim; Sung Hwan Jeong; Jin Hwa Lee; Moo Suk Park

doi:10.1111/j.1759-7714.2011.00107.x

Prevalence, risk factors and survival of lung cancer in the idiopathic pulmonary fibrosis

Kyung Jong Lee, Man Pyo Chung, Young Whan Kim, Jae Ho Lee, Kyu Sik Kim, Jeong Seon Ryu, Hong Lyeol Lee, Sung Woo Park, Choon Sik Park, Soo Tak Uh, Yong Chul Lee, Seoung Ju Park, Kwan Hyoung Kim, Young June Jeon, Won Il Choi, Yong Bum Park, Dong Soon Kim, Sung Hwan Jeong, Jin Hwa Lee, Moo Suk Park

Department of Internal Medicine

Research output: Contribution to journal › Article › peer-review

37 Scopus citations

Abstract

Background: The aim of this study was to evaluate the prevalence, risk factors, and survival of lung cancer in patients with idiopathic pulmonary fibrosis (IPF). Methods: IPF with lung cancer from tertiary hospitals consisted of 1685 patients who had been diagnosed between 2003 and 2007.We reviewed their medical records retrospectively to evaluate the prevalence, risk factors and prognosis of lung cancer in IPF patients. Results: Among all patients with IPF, 114 cases (6.8%) had lung cancer with IPF. The incidence of lung cancer in patients with IPF was 1.03 persons per 100 person-year (25 patients/2408 years). Most cases of lung cancer (73/114, 68.9%) were located in IPF-associated areas; the lung cancer typically developed in peripheral and lower lobe areas. The study revealed that forced vital capacity (%predicted) at the initial diagnosis and development of lung cancerwere independent prognostic factors in patients with IPF. Conclusions: Lung cancer in patientswith IPF was significantly relatedwith the IPF prognosis. An active evaluation should be performed in patients with IPF to detect lung cancer early.

Original language	English
Pages (from-to)	150-155
Number of pages	6
Journal	Thoracic Cancer
Volume	3
Issue number	2
DOIs	https://doi.org/10.1111/j.1759-7714.2011.00107.x
State	Published - May 2012

Keywords

Idiopathic pulmonary fibrosis
Lung cancer
Prevalence

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Lee, K. J., Chung, M. P., Kim, Y. W., Lee, J. H., Kim, K. S., Ryu, J. S., Lee, H. L., Park, S. W., Park, C. S., Uh, S. T., Lee, Y. C., Park, S. J., Kim, K. H., Jeon, Y. J., Choi, W. I., Park, Y. B., Kim, D. S., Jeong, S. H., Lee, J. H., & Park, M. S. (2012). Prevalence, risk factors and survival of lung cancer in the idiopathic pulmonary fibrosis. Thoracic Cancer, 3(2), 150-155. https://doi.org/10.1111/j.1759-7714.2011.00107.x

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title = "Prevalence, risk factors and survival of lung cancer in the idiopathic pulmonary fibrosis",

abstract = "Background: The aim of this study was to evaluate the prevalence, risk factors, and survival of lung cancer in patients with idiopathic pulmonary fibrosis (IPF). Methods: IPF with lung cancer from tertiary hospitals consisted of 1685 patients who had been diagnosed between 2003 and 2007.We reviewed their medical records retrospectively to evaluate the prevalence, risk factors and prognosis of lung cancer in IPF patients. Results: Among all patients with IPF, 114 cases (6.8%) had lung cancer with IPF. The incidence of lung cancer in patients with IPF was 1.03 persons per 100 person-year (25 patients/2408 years). Most cases of lung cancer (73/114, 68.9%) were located in IPF-associated areas; the lung cancer typically developed in peripheral and lower lobe areas. The study revealed that forced vital capacity (%predicted) at the initial diagnosis and development of lung cancerwere independent prognostic factors in patients with IPF. Conclusions: Lung cancer in patientswith IPF was significantly relatedwith the IPF prognosis. An active evaluation should be performed in patients with IPF to detect lung cancer early.",

keywords = "Idiopathic pulmonary fibrosis, Lung cancer, Prevalence",

author = "Lee, {Kyung Jong} and Chung, {Man Pyo} and Kim, {Young Whan} and Lee, {Jae Ho} and Kim, {Kyu Sik} and Ryu, {Jeong Seon} and Lee, {Hong Lyeol} and Park, {Sung Woo} and Park, {Choon Sik} and Uh, {Soo Tak} and Lee, {Yong Chul} and Park, {Seoung Ju} and Kim, {Kwan Hyoung} and Jeon, {Young June} and Choi, {Won Il} and Park, {Yong Bum} and Kim, {Dong Soon} and Jeong, {Sung Hwan} and Lee, {Jin Hwa} and Park, {Moo Suk}",

year = "2012",

month = may,

doi = "10.1111/j.1759-7714.2011.00107.x",

language = "English",

volume = "3",

pages = "150--155",

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Lee, KJ, Chung, MP, Kim, YW, Lee, JH, Kim, KS, Ryu, JS, Lee, HL, Park, SW, Park, CS, Uh, ST, Lee, YC, Park, SJ, Kim, KH, Jeon, YJ, Choi, WI, Park, YB, Kim, DS, Jeong, SH, Lee, JH & Park, MS 2012, 'Prevalence, risk factors and survival of lung cancer in the idiopathic pulmonary fibrosis', Thoracic Cancer, vol. 3, no. 2, pp. 150-155. https://doi.org/10.1111/j.1759-7714.2011.00107.x

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T1 - Prevalence, risk factors and survival of lung cancer in the idiopathic pulmonary fibrosis

AU - Lee, Kyung Jong

AU - Chung, Man Pyo

AU - Kim, Young Whan

AU - Lee, Jae Ho

AU - Kim, Kyu Sik

AU - Ryu, Jeong Seon

AU - Lee, Hong Lyeol

AU - Park, Sung Woo

AU - Park, Choon Sik

AU - Uh, Soo Tak

AU - Lee, Yong Chul

AU - Park, Seoung Ju

AU - Kim, Kwan Hyoung

AU - Jeon, Young June

AU - Choi, Won Il

AU - Park, Yong Bum

AU - Kim, Dong Soon

AU - Jeong, Sung Hwan

AU - Lee, Jin Hwa

AU - Park, Moo Suk

PY - 2012/5

Y1 - 2012/5

N2 - Background: The aim of this study was to evaluate the prevalence, risk factors, and survival of lung cancer in patients with idiopathic pulmonary fibrosis (IPF). Methods: IPF with lung cancer from tertiary hospitals consisted of 1685 patients who had been diagnosed between 2003 and 2007.We reviewed their medical records retrospectively to evaluate the prevalence, risk factors and prognosis of lung cancer in IPF patients. Results: Among all patients with IPF, 114 cases (6.8%) had lung cancer with IPF. The incidence of lung cancer in patients with IPF was 1.03 persons per 100 person-year (25 patients/2408 years). Most cases of lung cancer (73/114, 68.9%) were located in IPF-associated areas; the lung cancer typically developed in peripheral and lower lobe areas. The study revealed that forced vital capacity (%predicted) at the initial diagnosis and development of lung cancerwere independent prognostic factors in patients with IPF. Conclusions: Lung cancer in patientswith IPF was significantly relatedwith the IPF prognosis. An active evaluation should be performed in patients with IPF to detect lung cancer early.

AB - Background: The aim of this study was to evaluate the prevalence, risk factors, and survival of lung cancer in patients with idiopathic pulmonary fibrosis (IPF). Methods: IPF with lung cancer from tertiary hospitals consisted of 1685 patients who had been diagnosed between 2003 and 2007.We reviewed their medical records retrospectively to evaluate the prevalence, risk factors and prognosis of lung cancer in IPF patients. Results: Among all patients with IPF, 114 cases (6.8%) had lung cancer with IPF. The incidence of lung cancer in patients with IPF was 1.03 persons per 100 person-year (25 patients/2408 years). Most cases of lung cancer (73/114, 68.9%) were located in IPF-associated areas; the lung cancer typically developed in peripheral and lower lobe areas. The study revealed that forced vital capacity (%predicted) at the initial diagnosis and development of lung cancerwere independent prognostic factors in patients with IPF. Conclusions: Lung cancer in patientswith IPF was significantly relatedwith the IPF prognosis. An active evaluation should be performed in patients with IPF to detect lung cancer early.

KW - Idiopathic pulmonary fibrosis

KW - Lung cancer

KW - Prevalence

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U2 - 10.1111/j.1759-7714.2011.00107.x

DO - 10.1111/j.1759-7714.2011.00107.x

M3 - Article

AN - SCOPUS:84868116251

SN - 1759-7706

VL - 3

SP - 150

EP - 155

JO - Thoracic Cancer

JF - Thoracic Cancer

IS - 2

ER -

Prevalence, risk factors and survival of lung cancer in the idiopathic pulmonary fibrosis

Abstract

Keywords

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