Prevalence and patterns of Left Ventricular Hypertrophy in patients with predialysis Chronic Renal Failure

Sung Kyu Ha, Hong Su Park, Seung Jung Kim, Chong Hoon Park, Dong Su Kim, Hyun Seung Kim

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Left ventricular hypertrophy (LVH) is an independent risk factor for cardiac death. This study evaluates the prevalence and patterns of LVH in patients with predialysis chronic renal failure (CRF) and analyses the relationship between LVH and various predisposing factors. Sixty-two CRF patients were recruited from the renal clinic with serum creatinine over 2 mg/dl. Using echocardiography, we calculated the left ventricular mass index (LVMI) and relative wall thickness (RWT), and classified the patients into four groups (Group 1: normal, Group 2: concentric remodelling, Group 3: concentric hypertrophy, Group 4: eccentric hypertrophy). Prevalence and patterns of LVH in patients with CRF were as follows; 6.5% in Groups 1 and 2, 56.5% in Group 3 and 30.5% in Group 4. LVMI increases with progressive renal function decline. There were linear correlations between LVMI and systolic and diastolic blood pressure (BP), serum creatinine (Scr) and intact parathyroid hormone (PTH) in patients with predialysis CRF and also inverse linear correlations between LVMI and creatinine clearance (Ccr) and hemoglobin. In conclusion, we demonstrate the high prevalence of LVH (87%) in patients with predialysis CRF and concentric hypertrophy (56.5%) was the main pattern of LVH. Several factors such as anemia, systolic and diastolic BP, renal function and PTH influence LVMI.

Original languageEnglish
Pages (from-to)488-494
Number of pages7
JournalJournal of Korean Medical Science
Volume13
Issue number5
DOIs
StatePublished - Oct 1998

Keywords

  • Hypertrophy, left ventricular
  • Kidney failure, chronic

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