TY - JOUR
T1 - Prenatal maternal alcohol exposure
T2 - diagnosis and prevention of fetal alcohol syndrome
AU - Hur, Young Min
AU - Choi, Jiwon
AU - Park, Sunwha
AU - Oh, Sarah Soyeon
AU - Kim, Young Ju
N1 - Funding Information:
This study was supported by funding from the National Research Foundation of Korea (NRF-2020R1A2C3011850), and BK21 FOUR (Fostering Outstanding Universities for Research) was funded by the Ministry of Education and the NRF.
Publisher Copyright:
© 2022 Korean Society of Obstetrics and Gynecology
PY - 2022
Y1 - 2022
N2 - Fetal alcohol syndrome (FAS) is a developmental and congenital disorder characterized by neurocognitive impairment, structural defects, and growth restriction due to prenatal alcohol exposure. The estimated global prevalence of alcohol use during pregnancy is 9.8%, and the estimated prevalence of FAS in the general population is 14.6 per 10,000 people. In Korea, the estimated prevalence of alcohol use during pregnancy is 16%, and the prevalence of FAS is 18-51 per 10,000 women, which is higher than the global prevalence. Women’s alcohol consumption rates have increased, especially in women of childbearing age. This could increase the incidence of FAS, leading to higher medical expenses and burden on society. Alcohol is the single most important teratogen that causes FAS, and there is no safe trimester to drink alcohol and no known safe amount of alcohol consumption during pregnancy. Thus, physicians should assess women’s drinking patterns in detail and provide education on FAS to women by understanding its pathophysiology. Moreover, the prevention of FAS requires long-term care with a multidisciplinary approach.
AB - Fetal alcohol syndrome (FAS) is a developmental and congenital disorder characterized by neurocognitive impairment, structural defects, and growth restriction due to prenatal alcohol exposure. The estimated global prevalence of alcohol use during pregnancy is 9.8%, and the estimated prevalence of FAS in the general population is 14.6 per 10,000 people. In Korea, the estimated prevalence of alcohol use during pregnancy is 16%, and the prevalence of FAS is 18-51 per 10,000 women, which is higher than the global prevalence. Women’s alcohol consumption rates have increased, especially in women of childbearing age. This could increase the incidence of FAS, leading to higher medical expenses and burden on society. Alcohol is the single most important teratogen that causes FAS, and there is no safe trimester to drink alcohol and no known safe amount of alcohol consumption during pregnancy. Thus, physicians should assess women’s drinking patterns in detail and provide education on FAS to women by understanding its pathophysiology. Moreover, the prevention of FAS requires long-term care with a multidisciplinary approach.
KW - Alcohols
KW - Fetal alcohol spectrum disorders
KW - Fetal alcohol syndrome
KW - Pregnancy
UR - http://www.scopus.com/inward/record.url?scp=85138174455&partnerID=8YFLogxK
U2 - 10.5468/ogs.22123
DO - 10.5468/ogs.22123
M3 - Article
AN - SCOPUS:85138174455
SN - 2287-8572
VL - 65
SP - 385
EP - 394
JO - Obstetrics and Gynecology Science
JF - Obstetrics and Gynecology Science
IS - 5
ER -