TY - JOUR
T1 - Prenatal exposure to alcohol, tobacco and coffee
T2 - Associated congenital complications and adverse birth outcomes
AU - Oh, Sarah Soyeon
AU - Park, Sunwha
AU - You, Young Ah
AU - Jee, Yongho
AU - Ansari, Abuzar
AU - Kim, Soo Min
AU - Lee, Gain
AU - Kim, Young Ju
N1 - Funding Information:
Funding: This research was supported by the National Research Foundation (NRF) of Korea (NRF-2020R1A2C3011850) and BK21 Four (Fostering Outstanding Universities for Research), funded by the Ministry of Education and NRF.
Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/3/2
Y1 - 2021/3/2
N2 - A few studies to date have examined the association between prenatal exposure to alcohol, tobacco, and coffee, and congenital complications/adverse birth outcomes among South Korean populations. Thus, this study analyzed the data of 1675 Korean women with birth experience within the last 3 years for pregnancy-related health and nutritional behaviors and relative outcomes. During their pregnancies, 11.58% of the study population consumed alcohol at least once, 1.43% drank throughout all three trimesters, 1.13% smoked, 25.43% were exposed to secondhand smoking, and 28.18% consumed 3 coffees or more every day. Prenatal alcohol exposure was associated with 11.24 times increased risk of birth defects/disabilities [Odds Ratio (OR): 11.24, 95% Confidence Interval (CI) 1.07–117.86] and 10.66 times increased risk of inherited metabolic diseases (OR: 10.66, 95% CI: 1.08–104.82). Prenatal secondhand smoke exposure (OR: 1.62, 95% CI: 1.01–2.62) and coffee consumption (OR: 1.92, 95% CI: 1.22–3.03) was associated with increased risk of low birth weight. Such results were in alignment with that of previous studies and confirmed that prenatal alcohol, tobacco, and coffee exposure can have detrimental neonatal and maternal consequences.
AB - A few studies to date have examined the association between prenatal exposure to alcohol, tobacco, and coffee, and congenital complications/adverse birth outcomes among South Korean populations. Thus, this study analyzed the data of 1675 Korean women with birth experience within the last 3 years for pregnancy-related health and nutritional behaviors and relative outcomes. During their pregnancies, 11.58% of the study population consumed alcohol at least once, 1.43% drank throughout all three trimesters, 1.13% smoked, 25.43% were exposed to secondhand smoking, and 28.18% consumed 3 coffees or more every day. Prenatal alcohol exposure was associated with 11.24 times increased risk of birth defects/disabilities [Odds Ratio (OR): 11.24, 95% Confidence Interval (CI) 1.07–117.86] and 10.66 times increased risk of inherited metabolic diseases (OR: 10.66, 95% CI: 1.08–104.82). Prenatal secondhand smoke exposure (OR: 1.62, 95% CI: 1.01–2.62) and coffee consumption (OR: 1.92, 95% CI: 1.22–3.03) was associated with increased risk of low birth weight. Such results were in alignment with that of previous studies and confirmed that prenatal alcohol, tobacco, and coffee exposure can have detrimental neonatal and maternal consequences.
KW - Adverse birth outcomes
KW - Birth complications
KW - Fetal programming
KW - Maternal malnutrition
KW - Prenatal alcohol exposure
KW - Prenatal tobacco exposure
UR - http://www.scopus.com/inward/record.url?scp=85102611140&partnerID=8YFLogxK
U2 - 10.3390/ijerph18063140
DO - 10.3390/ijerph18063140
M3 - Article
C2 - 33803679
AN - SCOPUS:85102611140
SN - 1661-7827
VL - 18
SP - 1
EP - 8
JO - International Journal of Environmental Research and Public Health
JF - International Journal of Environmental Research and Public Health
IS - 6
M1 - 3140
ER -