Potentially bioactive two new natural sesquiterpenoids from the rhizomes of Zingiber zerumbet

Sik Jang Dae, Eun Kyoung Seo

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Repeated chromatography of the n-hexane-soluble fraction of the MeOH extract of the rhizomes of Zingiber zerumbet led to the isolation of two isomers of 6-methoxy-2E,9E-humuladien-8-one (1 and 2) and stigmast-4-en-3-one. The structures of 1 and 2 were determined by spectroscopic methods including 1D and 2D-NMR elucidated by analysis of spectroscopic data as well as by comparison with published values. This is the first report on the isolation of compounds 1 and 2 from the nature. Stigmast-4-en-3-one was first isolated from this plant.

Original languageEnglish
Pages (from-to)294-296
Number of pages3
JournalArchives of Pharmacal Research
Volume28
Issue number3
DOIs
StatePublished - 31 Mar 2005

Keywords

  • 6-Methoxy-2E,9E- humuladien-8-one
  • Sesquiterpenoids
  • Stigmast-4-en-3-one
  • Zingiber zerumbet
  • Zingiberaceae

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