Abstract
Repeated chromatography of the n-hexane-soluble fraction of the MeOH extract of the rhizomes of Zingiber zerumbet led to the isolation of two isomers of 6-methoxy-2E,9E-humuladien-8-one (1 and 2) and stigmast-4-en-3-one. The structures of 1 and 2 were determined by spectroscopic methods including 1D and 2D-NMR elucidated by analysis of spectroscopic data as well as by comparison with published values. This is the first report on the isolation of compounds 1 and 2 from the nature. Stigmast-4-en-3-one was first isolated from this plant.
| Original language | English |
|---|---|
| Pages (from-to) | 294-296 |
| Number of pages | 3 |
| Journal | Archives of Pharmacal Research |
| Volume | 28 |
| Issue number | 3 |
| DOIs | |
| State | Published - 31 Mar 2005 |
Bibliographical note
Funding Information:This study was supported by the Korea Science and Engineering Foundation for the National R&D Program for Enhancing R&D Infrastructure of Womens University \[R06-2002-011-01002-0(2002)\]. We are grateful to Prof. Tri Windono and Dr. Gwang-Ho Jeohn at Surabaya University, Surabaya, Indonesia for plant collection.
Keywords
- 6-Methoxy-2E,9E- humuladien-8-one
- Sesquiterpenoids
- Stigmast-4-en-3-one
- Zingiber zerumbet
- Zingiberaceae