Potential Utility of SPECT/CT for Early Detection of Spontaneous Osteonecrosis of the Knee

Min Young Yoo; Young Soo Shin; Ok Kyu Song; Bom Sahn Kim; Seo Young Kang; Byung Seok Moon; Hai Jeon Yoon

doi:10.1097/RLU.0000000000004312

Potential Utility of SPECT/CT for Early Detection of Spontaneous Osteonecrosis of the Knee

Min Young Yoo, Young Soo Shin, Ok Kyu Song, Bom Sahn Kim, Seo Young Kang, Byung Seok Moon, Hai Jeon Yoon

Department of Nuclear Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Spontaneous osteonecrosis of the knee (SONK) is the most common phenotype of osteonecrosis of knee joints in older adults. Early diagnosis with appropriate management is crucial for improving the prognosis of the SONK. We present SONK in bone scintigraphy and SPECT/CT in 65-year-old man with sudden worsening knee pain and normal radiographs. SPECT/CT revealed intense uptake in subchondral area of left femoral medial condyle, which can be differed from progressed osteoarthritic change of the knee joints suspected on planar scintigraphy. Subsequently performed MRI showed characteristic finding of SONK. Total knee replacement arthroplasty was performed with final histological diagnosis of SONK.

Original language	English
Pages (from-to)	E704-E705
Journal	Clinical Nuclear Medicine
Volume	47
Issue number	11
DOIs	https://doi.org/10.1097/RLU.0000000000004312
State	Published - 1 Nov 2022

Keywords

SPECT/CT
spontaneous osteonecrosis of the knee
subchondral lesion

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10.1097/RLU.0000000000004312

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title = "Potential Utility of SPECT/CT for Early Detection of Spontaneous Osteonecrosis of the Knee",

abstract = "Spontaneous osteonecrosis of the knee (SONK) is the most common phenotype of osteonecrosis of knee joints in older adults. Early diagnosis with appropriate management is crucial for improving the prognosis of the SONK. We present SONK in bone scintigraphy and SPECT/CT in 65-year-old man with sudden worsening knee pain and normal radiographs. SPECT/CT revealed intense uptake in subchondral area of left femoral medial condyle, which can be differed from progressed osteoarthritic change of the knee joints suspected on planar scintigraphy. Subsequently performed MRI showed characteristic finding of SONK. Total knee replacement arthroplasty was performed with final histological diagnosis of SONK.",

keywords = "SPECT/CT, spontaneous osteonecrosis of the knee, subchondral lesion",

author = "Yoo, {Min Young} and Shin, {Young Soo} and Song, {Ok Kyu} and Kim, {Bom Sahn} and Kang, {Seo Young} and Moon, {Byung Seok} and Yoon, {Hai Jeon}",

note = "Funding Information: Conflicts of interest and sources of funding: The authors declare that they have no conflicts of interest. This research was supported by grants from the Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Science and ICT (2021R1A2C1093636, H.-J.Y.; 2021R1F1A1060946, B.S.K.). Publisher Copyright: {\textcopyright} Wolters Kluwer Health, Inc. All rights reserved.",

year = "2022",

month = nov,

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doi = "10.1097/RLU.0000000000004312",

language = "English",

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T1 - Potential Utility of SPECT/CT for Early Detection of Spontaneous Osteonecrosis of the Knee

AU - Yoo, Min Young

AU - Shin, Young Soo

AU - Song, Ok Kyu

AU - Kim, Bom Sahn

AU - Kang, Seo Young

AU - Moon, Byung Seok

AU - Yoon, Hai Jeon

N1 - Funding Information: Conflicts of interest and sources of funding: The authors declare that they have no conflicts of interest. This research was supported by grants from the Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Science and ICT (2021R1A2C1093636, H.-J.Y.; 2021R1F1A1060946, B.S.K.). Publisher Copyright: © Wolters Kluwer Health, Inc. All rights reserved.

PY - 2022/11/1

Y1 - 2022/11/1

N2 - Spontaneous osteonecrosis of the knee (SONK) is the most common phenotype of osteonecrosis of knee joints in older adults. Early diagnosis with appropriate management is crucial for improving the prognosis of the SONK. We present SONK in bone scintigraphy and SPECT/CT in 65-year-old man with sudden worsening knee pain and normal radiographs. SPECT/CT revealed intense uptake in subchondral area of left femoral medial condyle, which can be differed from progressed osteoarthritic change of the knee joints suspected on planar scintigraphy. Subsequently performed MRI showed characteristic finding of SONK. Total knee replacement arthroplasty was performed with final histological diagnosis of SONK.

AB - Spontaneous osteonecrosis of the knee (SONK) is the most common phenotype of osteonecrosis of knee joints in older adults. Early diagnosis with appropriate management is crucial for improving the prognosis of the SONK. We present SONK in bone scintigraphy and SPECT/CT in 65-year-old man with sudden worsening knee pain and normal radiographs. SPECT/CT revealed intense uptake in subchondral area of left femoral medial condyle, which can be differed from progressed osteoarthritic change of the knee joints suspected on planar scintigraphy. Subsequently performed MRI showed characteristic finding of SONK. Total knee replacement arthroplasty was performed with final histological diagnosis of SONK.

KW - SPECT/CT

KW - spontaneous osteonecrosis of the knee

KW - subchondral lesion

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AN - SCOPUS:85139573196

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VL - 47

SP - E704-E705

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

IS - 11

ER -

Potential Utility of SPECT/CT for Early Detection of Spontaneous Osteonecrosis of the Knee

Abstract

Keywords

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