Potential Utility of SPECT/CT for Early Detection of Spontaneous Osteonecrosis of the Knee

Min Young Yoo, Young Soo Shin, Ok Kyu Song, Bom Sahn Kim, Seo Young Kang, Byung Seok Moon, Hai Jeon Yoon

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Spontaneous osteonecrosis of the knee (SONK) is the most common phenotype of osteonecrosis of knee joints in older adults. Early diagnosis with appropriate management is crucial for improving the prognosis of the SONK. We present SONK in bone scintigraphy and SPECT/CT in 65-year-old man with sudden worsening knee pain and normal radiographs. SPECT/CT revealed intense uptake in subchondral area of left femoral medial condyle, which can be differed from progressed osteoarthritic change of the knee joints suspected on planar scintigraphy. Subsequently performed MRI showed characteristic finding of SONK. Total knee replacement arthroplasty was performed with final histological diagnosis of SONK.

Original languageEnglish
Pages (from-to)E704-E705
JournalClinical Nuclear Medicine
Issue number11
StatePublished - 1 Nov 2022

Bibliographical note

Funding Information:
Conflicts of interest and sources of funding: The authors declare that they have no conflicts of interest. This research was supported by grants from the Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Science and ICT (2021R1A2C1093636, H.-J.Y.; 2021R1F1A1060946, B.S.K.).

Publisher Copyright:
© Wolters Kluwer Health, Inc. All rights reserved.


  • spontaneous osteonecrosis of the knee
  • subchondral lesion


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