Postoperative Deep Infection After Cemented Versus Cementless Total Hip Arthroplasty: A Meta-Analysis

Byung Ho Yoon; Yong Chan Ha; Young Kyun Lee; Kyung Hoi Koo

doi:10.1016/j.arth.2015.04.041

Postoperative Deep Infection After Cemented Versus Cementless Total Hip Arthroplasty: A Meta-Analysis

Byung Ho Yoon, Yong Chan Ha, Young Kyun Lee, Kyung Hoi Koo

Department of Orthopedic Surgery

Research output: Contribution to journal › Review article › peer-review

30 Scopus citations

Abstract

Periprosthetic joint infection (PJI) is a serious complication of total hip arthroplasty (THA). The objective of this meta-analysis was to compare the PJI rate between cemented and cementless THAs. Eight clinical studies (2 randomized controlled trials and 6 observational studies) were available for the analysis. Meta-analysis (with a fixed-effects model) and subgroup analysis were performed by research design and meta-regression was performed by continuous moderator. The overall incidence of PJI was 0.4% (357/84,200). The incidence was 0.5% (310/67,531) in cemented group, and 0.3% (47/16,669) in cementless group (P= 0.008). The meta-analysis revealed that the use of cement in THA was associated with an increased risk of PJI (odds ratio 1.53; 95% confidence interval 1.120 to 2.100; P= 0.008).

Original language	English
Pages (from-to)	1823-1827
Number of pages	5
Journal	Journal of Arthroplasty
Volume	30
Issue number	10
DOIs	https://doi.org/10.1016/j.arth.2015.04.041
State	Published - 1 Oct 2015

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc.

Keywords

Cemented
Cementless
Infection
Meta-analysis
Total hip arthroplasty

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10.1016/j.arth.2015.04.041

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title = "Postoperative Deep Infection After Cemented Versus Cementless Total Hip Arthroplasty: A Meta-Analysis",

abstract = "Periprosthetic joint infection (PJI) is a serious complication of total hip arthroplasty (THA). The objective of this meta-analysis was to compare the PJI rate between cemented and cementless THAs. Eight clinical studies (2 randomized controlled trials and 6 observational studies) were available for the analysis. Meta-analysis (with a fixed-effects model) and subgroup analysis were performed by research design and meta-regression was performed by continuous moderator. The overall incidence of PJI was 0.4% (357/84,200). The incidence was 0.5% (310/67,531) in cemented group, and 0.3% (47/16,669) in cementless group (P= 0.008). The meta-analysis revealed that the use of cement in THA was associated with an increased risk of PJI (odds ratio 1.53; 95% confidence interval 1.120 to 2.100; P= 0.008).",

keywords = "Cemented, Cementless, Infection, Meta-analysis, Total hip arthroplasty",

author = "Yoon, {Byung Ho} and Ha, {Yong Chan} and Lee, {Young Kyun} and Koo, {Kyung Hoi}",

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year = "2015",

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doi = "10.1016/j.arth.2015.04.041",

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T2 - A Meta-Analysis

AU - Yoon, Byung Ho

AU - Ha, Yong Chan

AU - Lee, Young Kyun

AU - Koo, Kyung Hoi

PY - 2015/10/1

Y1 - 2015/10/1

N2 - Periprosthetic joint infection (PJI) is a serious complication of total hip arthroplasty (THA). The objective of this meta-analysis was to compare the PJI rate between cemented and cementless THAs. Eight clinical studies (2 randomized controlled trials and 6 observational studies) were available for the analysis. Meta-analysis (with a fixed-effects model) and subgroup analysis were performed by research design and meta-regression was performed by continuous moderator. The overall incidence of PJI was 0.4% (357/84,200). The incidence was 0.5% (310/67,531) in cemented group, and 0.3% (47/16,669) in cementless group (P= 0.008). The meta-analysis revealed that the use of cement in THA was associated with an increased risk of PJI (odds ratio 1.53; 95% confidence interval 1.120 to 2.100; P= 0.008).

AB - Periprosthetic joint infection (PJI) is a serious complication of total hip arthroplasty (THA). The objective of this meta-analysis was to compare the PJI rate between cemented and cementless THAs. Eight clinical studies (2 randomized controlled trials and 6 observational studies) were available for the analysis. Meta-analysis (with a fixed-effects model) and subgroup analysis were performed by research design and meta-regression was performed by continuous moderator. The overall incidence of PJI was 0.4% (357/84,200). The incidence was 0.5% (310/67,531) in cemented group, and 0.3% (47/16,669) in cementless group (P= 0.008). The meta-analysis revealed that the use of cement in THA was associated with an increased risk of PJI (odds ratio 1.53; 95% confidence interval 1.120 to 2.100; P= 0.008).

KW - Cemented

KW - Cementless

KW - Infection

KW - Meta-analysis

KW - Total hip arthroplasty

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JO - Journal of Arthroplasty

JF - Journal of Arthroplasty

IS - 10

ER -

Postoperative Deep Infection After Cemented Versus Cementless Total Hip Arthroplasty: A Meta-Analysis

Abstract

Bibliographical note

Keywords

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