Polymeric nanoparticles for protein kinase activity

Jong Ho Kim, Seulki Lee, Kwangmeyung Kim, Hyesung Jeon, Rang Woon Park, In San Kim, Kuiwon Choi, Ick Chan Kwon

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Nanoparticles were prepared from poly-ion complexes, possessing both PEI-FITC-(PKA-specific substrate) (kemptide) and PAA-TRITC, which produce intermolecular FRET; the nanoparticles were dissociated by phosphorylation, presented a strong FITC intensity and can be applied to high-throughput screening for large chemical libraries, for drug discovery of kinase inhibitors.

Original languageEnglish
Pages (from-to)1346-1348
Number of pages3
JournalChemical Communications
Issue number13
StatePublished - 2007


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