TY - JOUR
T1 - Polydopamine, harness of the antibacterial potentials-A review
AU - He, Xiaojun
AU - Obeng, Enoch
AU - Sun, Xiaoshuai
AU - Kwon, Nahyun
AU - Shen, Jianliang
AU - Yoon, Juyoung
N1 - Publisher Copyright:
© 2022 The Authors
PY - 2022/6
Y1 - 2022/6
N2 - Antibiotic resistance is one of the major causes of morbidity and mortality, triggered by the adhesion of microbes and to some extent the formation of biofilms. This condition has been quite challenging in the health and industrial sector. Conditions and processes required to foil these infectious and resistance are of much concern. The synthesis of PDA material, inspired by the Mytilus edulis foot protein (MEFP)5 possesses unique characteristics that allow for, adhesion, photothermal therapy, synergistic effects with other materials, biocompatibility process, etc. Therefore, their usage holds great potential for dealing with both the infectious nature and the antibiotic resistance processes. Hence, this review provides an overview of the mechanism involved in accomplishing and eradicating bacteria, the recently harnessed antibacterial effect of the PDA through other properties they possess, a way forward in tapping the benefit embedded in the PDA, and the future perspective.
AB - Antibiotic resistance is one of the major causes of morbidity and mortality, triggered by the adhesion of microbes and to some extent the formation of biofilms. This condition has been quite challenging in the health and industrial sector. Conditions and processes required to foil these infectious and resistance are of much concern. The synthesis of PDA material, inspired by the Mytilus edulis foot protein (MEFP)5 possesses unique characteristics that allow for, adhesion, photothermal therapy, synergistic effects with other materials, biocompatibility process, etc. Therefore, their usage holds great potential for dealing with both the infectious nature and the antibiotic resistance processes. Hence, this review provides an overview of the mechanism involved in accomplishing and eradicating bacteria, the recently harnessed antibacterial effect of the PDA through other properties they possess, a way forward in tapping the benefit embedded in the PDA, and the future perspective.
KW - Antibacterial activity
KW - Antibiotic resistance
KW - Biofilm
KW - Nanoparticle
KW - Polydopamine
UR - http://www.scopus.com/inward/record.url?scp=85132920909&partnerID=8YFLogxK
U2 - 10.1016/j.mtbio.2022.100329
DO - 10.1016/j.mtbio.2022.100329
M3 - Review article
AN - SCOPUS:85132920909
SN - 2590-0064
VL - 15
JO - Materials Today Bio
JF - Materials Today Bio
M1 - 100329
ER -