Polydopamine, harness of the antibacterial potentials-A review

Xiaojun He, Enoch Obeng, Xiaoshuai Sun, Nahyun Kwon, Jianliang Shen, Juyoung Yoon

Research output: Contribution to journalReview articlepeer-review

36 Scopus citations


Antibiotic resistance is one of the major causes of morbidity and mortality, triggered by the adhesion of microbes and to some extent the formation of biofilms. This condition has been quite challenging in the health and industrial sector. Conditions and processes required to foil these infectious and resistance are of much concern. The synthesis of PDA material, inspired by the Mytilus edulis foot protein (MEFP)5 possesses unique characteristics that allow for, adhesion, photothermal therapy, synergistic effects with other materials, biocompatibility process, etc. Therefore, their usage holds great potential for dealing with both the infectious nature and the antibiotic resistance processes. Hence, this review provides an overview of the mechanism involved in accomplishing and eradicating bacteria, the recently harnessed antibacterial effect of the PDA through other properties they possess, a way forward in tapping the benefit embedded in the PDA, and the future perspective.

Original languageEnglish
Article number100329
JournalMaterials Today Bio
StatePublished - Jun 2022

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  • Antibacterial activity
  • Antibiotic resistance
  • Biofilm
  • Nanoparticle
  • Polydopamine


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