Polydopamine, harness of the antibacterial potentials-A review

Xiaojun He, Enoch Obeng, Xiaoshuai Sun, Nahyun Kwon, Jianliang Shen, Juyoung Yoon

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Antibiotic resistance is one of the major causes of morbidity and mortality, triggered by the adhesion of microbes and to some extent the formation of biofilms. This condition has been quite challenging in the health and industrial sector. Conditions and processes required to foil these infectious and resistance are of much concern. The synthesis of PDA material, inspired by the Mytilus edulis foot protein (MEFP)5 possesses unique characteristics that allow for, adhesion, photothermal therapy, synergistic effects with other materials, biocompatibility process, etc. Therefore, their usage holds great potential for dealing with both the infectious nature and the antibiotic resistance processes. Hence, this review provides an overview of the mechanism involved in accomplishing and eradicating bacteria, the recently harnessed antibacterial effect of the PDA through other properties they possess, a way forward in tapping the benefit embedded in the PDA, and the future perspective.

Original languageEnglish
Article number100329
JournalMaterials Today Bio
StatePublished - Jun 2022

Bibliographical note

Funding Information:
This work was financially supported by the National Natural Science Foundation of China ( 21977081 ), Zhejiang Provincial Natural Science of Foundation of China ( LZ19H180001 ), University of Chinese Academy of Science ( WIBEZD2017001-03 ), Wenzhou Science and Technology Plan Project ( ZG2021035 ), Wenzhou Medical University ( KYYW201901 ). Zhejiang Qianjiang Talent Plan ( QJD20020224 ), J. Yoon thanks to Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education ( 2021R1A6A1A10039823 ).

Publisher Copyright:
© 2022 The Authors


  • Antibacterial activity
  • Antibiotic resistance
  • Biofilm
  • Nanoparticle
  • Polydopamine


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