Platelet-derived growth factor-induced H₂O₂ production requires the activation of phosphatidylinositol 3-kinase

Medicine & Life Sciences

• Platelet-Derived Growth Factor 96%
• Phosphatidylinositol 3-Kinase 84%
• Phosphatidylinositols 68%
• Phosphotransferases 64%
• Type C Phospholipases 30%
• ras GTPase-Activating Proteins 29%
• Platelet-Derived Growth Factor Receptors 24%
• Binding Sites 14%
• GTPase-Activating Proteins 12%
• ras Proteins 11%
• Phosphotyrosine 11%
• Wortmannin 11%
• Protein Tyrosine Phosphatases 11%
• src Homology Domains 11%
• 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one 10%
• NADPH Oxidases 10%
• Hep G2 Cells 9%
• Tyrosine 8%
• Enzymes 5%

Chemical Compounds

• Phosphatidylinositol 100%
• LY294002 25%
• Phosphatidylinositol 3 Kinase Inhibitor 23%
• Wortmannin 23%
• Binding Site 19%
• Protein 17%
• Tyrosine Residue 15%
• Effector 15%
• Tyrosine 12%