Plasmon resonance energy transfer-based ultrafast PCR

Doyeon Bang, Jonghwan Lee, Luke P. Lee

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Plasmon resonance energy transfer (PRET), a highly efficient nanoscale radiationless transfer of energy in the form of plasmon enabled measurement of the nanoscale quantized phenomenon. Here, we utilized the PRET principle to accomplish an ultrafast PCR system using a hexagonally-assembled nanocrescent antenna (HANA), which resonates in the near-infrared region (860 nm) to maximize RET efficiency with a low power excitation light source (3W, diode). We accomplished experimentally ultrafast on-chip thermal cycling (56s / 30 cycles, heat up from 68 °C to 92 °C in 370 ms and peak of dT/dt > 75).

Original languageEnglish
Title of host publication22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PublisherChemical and Biological Microsystems Society
Pages301-304
Number of pages4
ISBN (Electronic)9781510897571
StatePublished - 2018
Event22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 - Kaohsiung, Taiwan, Province of China
Duration: 11 Nov 201815 Nov 2018

Publication series

Name22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Volume1

Conference

Conference22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Country/TerritoryTaiwan, Province of China
CityKaohsiung
Period11/11/1815/11/18

Bibliographical note

Funding Information:
This research was supported by Global Research Laboratory (GRL) Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science and ICT (Grant No: 2013K1A1A2A02050616) and PCARI-CHED (Grant No: 131).

Publisher Copyright:
Copyright© (2018) by Chemical and Biological Microsystems Society.All rights reserved.

Keywords

  • Molecular diagnostics
  • Plasmon resonance energy transfer
  • Polymerase chain reaction (PCR)
  • Surface plasmon resonance

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