Phytochemicals and bioactivities of zingiber cassumunar roxb

Ah Reum Han, Hyunyoung Kim, Donglan Piao, Chan Hun Jung, Eun Kyoung Seo

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations


Zingiber cassumunar Roxb. (Zingiberaceae), is an important medicinal plant known as “Plai (Phlai)” in Thailand, “Bangle” in Indonesia, and “Bulei” in China. Traditionally, this plant has been used to treat inflammation, pain, and respiratory problems. The rhizomes are the primary part of the plant that has been used for medicinal purposes due to their constituents with therapeutic properties, including phenylbutenoids, curcuminoids, and essential oils. Since the 1970s, many studies have been conducted on the phytochemicals and bioactivities of Z. cassumunar to establish fundamental scientific evidence that supports its use in traditional medicine. The accumulated biological studies on the extracts, solvent fractions, and constituents of Z. cassumunar have described their diverse medicinal properties, including antioxidant, anti-inflammatory, anticancer, neuroprotective/neurotrophic, cosmeceutical, and antifungal/antimicrobial bioactivities. In this review, we summarize information on the phytochemicals of Z. cassumunar and the bioactivities of its extracts and constituents.

Original languageEnglish
Article number2377
Issue number8
StatePublished - 2 Apr 2021

Bibliographical note

Publisher Copyright:
Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland.


  • Anti-inflammation
  • Anticancer
  • Antioxidant
  • Cosmeceutical property
  • Curcuminoid
  • Essential oil
  • Neurotrophic activity
  • Phenylbutenoid
  • Zingiber cassumunar
  • Zingiberaceae


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