Phthalocyanines as medicinal photosensitizers: Developments in the last five years

Xingshu Li, Bing De Zheng, Xiao Hui Peng, Song Zi Li, Jia Wen Ying, Yuanyuan Zhao, Jian Dong Huang, Juyoung Yoon

Research output: Contribution to journalReview articlepeer-review

357 Scopus citations

Abstract

Owing to their high extinction coefficients, long absorption wavelengths, and modification tunable photophysical and photochemical properties, phthalocyanines (Pcs) have been widely used as photosensitizers for photodynamic therapy (PDT). Advances made in the past five years on the development of Pcs as medicinal photosensitizers are reviewed and the main design considerations for medicinal applications of these substances are discussed.

Original languageEnglish
Pages (from-to)147-160
Number of pages14
JournalCoordination Chemistry Reviews
Volume379
DOIs
StatePublished - 15 Jan 2019

Bibliographical note

Funding Information:
This Study was financially supported by the National Natural Science Foundation of China (Grant Nos. 21473033 , 21172037 ), Specialized Research Fund for the Doctoral Program of Higher Education (Grant No. 201135141001 ), and a grant from the National Creative Research Initiative programs of the National Research Foundation of Korea (NRF) funded by the Korean government (MSIP) (No. 2012R1A3A2048814 ).

Funding Information:
This Study was financially supported by the National Natural Science Foundation of China (Grant Nos. 21473033, 21172037), Specialized Research Fund for the Doctoral Program of Higher Education (Grant No. 201135141001), and a grant from the National Creative Research Initiative programs of the National Research Foundation of Korea (NRF) funded by the Korean government (MSIP) (No. 2012R1A3A2048814).

Publisher Copyright:
© 2017 Elsevier B.V.

Keywords

  • Medicinal
  • Photodynamic therapy
  • Photosensitizer
  • Phthalocyanine
  • Targeting
  • Water soluble

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