Phthalocyanines as contrast agents for photothermal therapy

Bing De Zheng, Qin Xue He, Xingshu Li, Juyoung Yoon, Jian Dong Huang

Research output: Contribution to journalReview articlepeer-review

116 Scopus citations


Phthalocyanine, as a type of organic photothermal agent, has advantages including a definite chemical structure, repeatable synthesis, strong absorption in the near-infrared region, tunable photophysical and photochemical properties, and inherent biodegradability. This review focuses on the recent progress made in the application of phthalocyanines as contrast agents for photothermal therapy (PTT). The present review not only discusses the molecular and/or supramolecular design considerations for enhancing the PTT effect of phthalocyanines, but also provides the perspectives and challenges of the use of phthalocyanines as contrast agents for PTT.

Original languageEnglish
Article number213548
JournalCoordination Chemistry Reviews
StatePublished - 1 Jan 2021

Bibliographical note

Publisher Copyright:
© 2020 Elsevier B.V.


  • Molecular stacking
  • Nanostructure
  • Photoinduced electron transfer
  • Photothermal therapy
  • Phthalocyanine


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